Research interests
Mark Mullee has a portfolio of 150+ publications, many in high impact internationally recognised peer-reviewed journals, including The New England Journal of Medicine, The Lancet, British Medical Journal, Annals of Internal Medicine and British Journal of Surgery. Several articles have been cited >200 times.
He is co-author of the paper “Delayed antibiotic prescribing strategies for respiratory tract infections in primary care: pragmatic, factorial, randomised controlled trial”. It was one of five publications selected as finalists in the category of “Research Paper of the Year” for the British Medical Journal Research Awards 2015. Mark Mullee was involved in the research design, analysis of the data and writing of the research paper as well being a co-application of the research grant.
Selection of Recent papers:
1. Kennedy CR, McCann DC, Campbell MJ, Law CM, Mullee M, Petrou S, Watkin P, Worsfold S, Yuen HM, Stevenson J. Language ability after early detection of permanent childhood hearing impairment. New England Journal of Medicine, 2006, 354 (20), 2131-2141.
2. Birmingham L, Coulson D, Mullee M, Kamal M, Gregoire A. The mental health of women in prison mother and baby units. Journal of Forensic Psychiatry & Psychology, 2006, 17(3), 393-404.
3. Williamson I, Benge S, Mullee M A, Little P. Consultations for middle ear disease, antibiotic prescribing and risk factors for reattendance: a case-linked cohort study. British Journal of General Practice, 2006, 56(524), 170-175.
4. Little P, Turner S, Rumsby K, Warner G, Moore M, Lowes JA, Smith H, Hawke C, Mullee M. Developing clinical trial rules to predict urinary trial infection in primary care settings: sensitivity and specificity of near patient tests (dipsticks) and clinical scores. British Journal of General Practice, 2006, 56 (529), 606-612.
5. George S, Primrose J, Talbot R, Smith J, King P, Mullee M, Bailey D, du Boulay C, Jordan H. On behalf of the Wessex Colorectal Cancer Working Group. Will Rogers revisited: prospective observational study of survival of 3592 patients with colorectal cancer according to number of nodes examined by pathologists. British Journal of Cancer, 2006, 95 (7), 841-847.
6. Gibson D, Bruton A, Lewith GT, Mullee MA. Effects of acupuncture as a treatment for hyperventilation syndrome: A pilot randomized crossover trial. Journal of Alternative and Complimentary Medicine, 2007, 13 (1), 39-46
7. Kaushik A, Mullee M, Bryant T, Hill CM. A study of the association between children’s access to drinking water in primary schools and their fluid intake: Can water be ‘cool’ in school?. Child Care Health and Development, 2007, 33 (4), 409-415.
8. Guzder RN, Gatling W, Mullee MA, Byrne CD. Early mortality from the time of diagnosis of Type 2 diabetes: a 5-year prospective cohort study with a local age- and sex-matched comparison cohort. Diabetic Medicine, 2007, 24 (10), 1164-1167.
9. Julious SA, Mullee MA. Issues with using baseline in a last observation carried forward analysis. Pharmaceutical Statistics. 2008, 7 (2), 142-146.
10. Adams J, Burridge J, Mullee M, Hammond A, Cooper C. The clinical effectiveness of static resting splints in early rheumatoid arthritis: a randomized controlled trial. Rheumatology, 2008; 47 (10), 1548-1553.
11. Mullee M A, Briggs R S, Turnbull J C, Coleman PC and Stevenson J E. Self-rated activity levels and longevity: Evidence from a 20 year longitudinal study. International Journal of Ageing & Human Development. 2008, 67 (2), 171-186.
12. Armstrong B, Walthall H, Clancy M, Mullee M, Simpson H. Recording of vital signs in a district general hospital emergency department. Emergency Medicine Journal, 2008, 25 (12), 799-802.
13. Bethell HJN, Glover JD, Evans JA, Turner SC, Mehta RL, Mullee MA. The relationship between BNP and risk assessment in cardiac rehabilitation. British Journal of Cardiology, 2008, 15(3), 161-165.
14. Moore M, Yuen HM, Dunn N, Mullee MA, Maskell J, Kendrick T. Explaining the rise in antidepressant prescribing. A descriptive study using the General Practice Research Database. BMJ, 2009,339:b3999
15. Turner DA, Little PS, Turner S, Raftery J, Smith HE, Arscott A, Rumsby K, Mullee MA. Cost-effectiveness of management strategies for urinary tract infections: results from a randomized controlled trial. BMJ, 2010, 340: c346.
16. Little P, Moore M, Turner S, Rumsby K, Warner G, Lowes JA, Smith H, Hawke C, Leydon G, Ascot M, Turner D, Mullee M. Effectiveness of five different approaches in management of urinary tract infection: a randomised controlled trial. BMJ, 2010;340:c199.
17. Adams J, Mullee M, Burridge J, Hammond A, Cooper C. Responsiveness of self-report and therapist-rated upper extremity structural impairment and functional outcome measures in early rheumatoid arthritis. Arthritis Care & Research, 2010, 62(2): 274-278.
18. Gregoire A, Birmingham L, Mullee M, Dolan R, Coulson D. The mental health and treatment needs of imprisoned mothers of young children. Journal of Forensic Psychiatry & Psychology, 2010, 21(3): 378-392.
19. Yardley L, Barker F, Muller I, Turner D, Kirby S, Mullee M, Morris A, Little P. Clinical and cost-effectiveness of booklet based vestibular rehabilitation for chronic dizziness in primary care: a single blind, parallel group, pragmatic randomised controlled trial. BMJ 2012;344:e2237
20. Little P, Hobbs R, Mant D, McNulty CAM, Mullee M on behalf of the PRISM investigators. Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study. British Journal of General Practice 2012; e787
21. Little P, Stuart B, Moore M, Coenen S, Butler C, Godycki-Cwirko M, Mierzecki A, Chlabicz S, Torres T, Almirall J, Davies M, Schaberg T, Molstad S, Blasi F, DE Sutter A, Kersnik J, Hupkova H, Touboul P, Hood K, Mullee M, O’Reilly G, Brigman C, Goossens H, Verheij T on behalf of the GRACE consortium. Amoxicillin for acute lower respiratory tract infection in primary care when pneumonia is suspected: 12-country, randomized, placebo-controlled trial. The Lancet Infectious Diseases 2013, 13(2): 123-129.
22. Little P, Stuart B, Hobbs FD, Butler CC, Hay AD, Campbell J, Delaney B, Broomfield S, Barratt P, Hood Kerenza, Everitt, Mullee M, Williamson I, Mant D, Moore, M on behalf of DESCARTE investigators. Predictors of suppurative complications for acute sore throat in primary care: prospective clinical cohort study. BMJ 2013;347:f6867
23. Little P, Moore M, Kelly J, Williamson I, Leydon G, McDermott L, Mullee M, Stuart B on behalf of the PIPS investigators. Ibuprofen, paracetamol, and steam for Patients with respiratory tract infections in primary care: a pragmatic randomised factorial trial. BMJ 2013;347:f6041
24. Little P, Hobbs FDR, Moore M, Mant D, Williamson I, Delaney B, MCNulty C, Cheng MY, Leydon G, McManus R, Kelly J, Barnett, Glasziou P, Mullee M on behalf of the PRISM investigators. PRISM (PRImary care Streptococcal Management). Clinical Score and rapid antigen detection test to guide antibiotic use for sore throats: randomized controlled trial of PRISM (primary streptococcal management). BMJ 2013;347:f5806
25. Little P, Stuart B, Francis N Douglas E, Tonkin-Crine S, Anthierens S, Cals JWL, Melbye H, Santer M, Moore M, Coenen S, Butler C, Hood K, Kelly M, Godycki-Cwirko M, Mierzecki A, Torres A, Llor C, Davies M, Mullee M, O’Reilly G, van der Velden A, Geraghty AWA, Goossens H. Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomized, factorial, controlled trial. The Lancet 2013;382:1175-1182.
26. Little P, Moore M, Kelly J, Williamson I, Leydon G, McDermott, Mullee M, Stuart B on behalf of the PIPS investigators. Delayed antibiotic prescribing strategies for respiratory tract infections in primary care: pragmatic factorial, randomized controlled trial. BMJ 2014;348:g1606
27. Little P, Stuart B, Hobbs R, Butler CC, Hay AD, Delaney B, Campbell J, Broomfield S, Barratt P, Hood K, Everitt H, Mullee M, Williamson I, Mant D, Moore M on behalf of the DESCARTE investigators. Antibiotic prescription strategies for acute sore-throat: a prospective observational cohort study. Lancet Infectious Diseases 2014;14(3):213-219.
28. Summers R, Moore M, Byrne J, Byrne C, Mullee M A, Welbourn R, Elsey H, Roderick P. Perceptions of weight, diabetes and willingness to participate in randomised controlled trials of bariatric surgery for patients with type 2 diabetes mellitus and body mass index 30-39.9kg/m2. Obesity Surgery 2015, 25:1039–1046
29. Little P, Stuart B, Hobbs FDR, Moore M, Barnett J, Popoola D, Middleton K, Kelly J, Mullee M, Raftery J, Yao G, Carman W, Fleming D, Stokes-Lampard H, Williamson I, Joseph J, Miller S, Yardley L. An internet-delivered handwashing intervention to modify influenza-like illness and respiratory infection transmission (PRIMIT): a primary care randomised trial. Lancet, 2015, 386: 1631-39.
30. Marshall A, Spreadbury J, Cheston R, Coleman P, Ballinger C, Mullee M, Pritchard J, Russell C, Bartlett E. A pilot randomised controlled trial to compare changes in quality of life for participants with early diagnosis dementia who attend a ‘Living Well with Dementia’ group compared to waiting-list control. Aging & Mental Health, 2015, 19:6, 526-535
Mark Mullee has been a co-applicant on the these recent successful grant applications
:
NIHR
£5.3M awarded 2012
Mullee M
, Ballinger C, Jenkinson C, Boulton M, George S, Luengo-Fernandez R, Markham C, Yu L-M, Pradha n F, Jones J, Pallikadavath S.
NIHR Research Design Service South Central
BUPA
£230,000 awarded 2011
Clarke S, Faust S, Jeffries J, Roderick P,
Mullee M
, Moore M.
Optimising sample collection to detect carriage of Streptococcus pneumonia and other pathogenic bacteria in the upper respiratory tract – a pilot study.
NIHR RfPB
£249,624 awarded 2010
Burridge J, Yardley L, Jenkinson D, Hughes A-M,
Mullee M
, Weal M. Turner D.
Development and pilot evaluation of a web-supported programme of Constraint Induced Therapy following stroke (LifeCIT).
NIHR/MRC EME
£973,304 awarded 2010
Ottensmeier C, Rezvani K, Stevenson F, Williams T, Orchard K,
Mullee M
, Moore E, Marin-Costa D, Goldman J, Anstee D.
A novel anti-Wilms-Tumour-1 (WT1) vaccination strategy in haematological malignancy using DNA fusion vaccines delivered with electroporation.
NIHR Programme Grant for Applied Research
£1,999,790 awarded 2009
Sonuga-Barke E, Thompson M, Daley D, Coghill D, Barton J, Chen W, Latter S, Turner D, Tolcher R,
Mullee M
, George S, Laver-Bradbury C.
The development of an integrated early detection and intervention model for Attention Deficit Hyperactive Disorder.
NIHR RfPB
£212,914 awarded 2009
Roderick P, Byrne J, Elsey H, Byrne C, Moore M, Welbourn R,
Mullee M.
Optimum care for non-morbidly obese patients with type 2 diabetes: the perspectives of patients and clinicians on the role of bariatric surgery
HTA Clinical Trials
£2,627,333 awarded 2009
Thursz M,
Mullee M
, Donaldson C, Roderick P, Austin A, O’Grady J, Day C, Forrest E, Ryder S, Stewart S, Alison M.
STeroids or Pentoxifyline for Alcoholic Hepatitis (STOPAH) Trial.
NIHR Programme Grant for Applied Research
£1,358,275 awarded 2008
Arden N, Carr A, Cooper C, Price A, Javaid M, Beard D, Clarke N, Raftery J, Murray D,
Mullee M
, Price C.
Lower limb arthroplasty: can we predict outcome and failure and is it cost effective?
NIHR RfPB
£248,987 awarded 2008
Gray J, Bate J, Heath P, Clarke S, Faust S,
Mullee M
, Chisholm J.
Investigating the clinical use of 13-valent pneumococcal conjugate vaccine in childhood Acute Lymphoblastic Leukaemia
MRC
£1,501,889 awarded 2007
Little P, Yardley L, Hobbs R, Moore M, Williamson I,
Mullee M
, Wills G, Raftery J, Flemimg D, Carman W.
A PRimary care trial of an Infection control website to Modify Influenza-like illness (ILI) and RTI Transmission
Cancer Research UK
£161,500 awarded 2006
NIHR PGfAR
£1.999,372 awarded 2009
Little P,
Mullee M
, George S, Raftery J, Moore M, Williamson I, Yardley L, Leydon G, Wills G, Mant D, Tolcher R, Glasziou P.
PRimary care Infection Management for Everyday practice (PRIME)
Department(s)
Primary Care, Population Sciences and Medical Education
Research project(s)
A primary care trial of a website based infection control intervention to modify influenza-like illness and respiratory infection transmission.
