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Infrormation for participants and patients interested in taking part in CVLP trials.
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Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
Home
Hospitals Involved
Supported Vaccine Trials
Participants
CVLP Site Resources
Media and News Coverage
A study for patients with cancer who may be able to take part in research trials for personalised cancer vaccines.
Research Sites
Information and resources for sites taking part in the CVLP and CVLP trials.
What is the NHS Cancer Vaccine Launch Pad (CVLP)?
Background and study aim
CVLP status - Recruiting
The NHS Cancer Vaccine Launch Pad (CVLP) is a national study about finding people who may be able to take part in research trials for vaccines to treat cancer.
Vaccines are usually used to stop people from getting a disease, such as polio or measles immunisations. Researchers are now looking at using vaccines to stop cancer coming back after it has already been treated. Cancer vaccines stimulate the body’s immune system to recognise and attack cancer cells.
Cancer vaccines are being tested in research trials to understand how well they work. By supporting these trials, NHS England aims to speed up the development of vaccine treatments for cancer patients. If successful, cancer vaccines could become part of standard of care for cancer.
Which research trials of cancer vaccines are supported by the NHS Cancer Vaccine Launch Pad?
Currently, the NHS Cancer Vaccine Launch Pad is supporting one vaccine trial in colorectal cancer.
Who can participate?
At the moment, people who have been diagnosed with colorectal cancer are being invited to take part in the NHS Cancer Vaccine Launch Pad if they are receiving care at a hospital that is participating in the NHS Cancer Vaccine Launch Pad and if their cancer is at a particular stage.
Patients recruited - 274
As the NHS Cancer Vaccine Launch Pad starts to support more vaccine trials, patients with different cancer types will be invited to take part in the NHS Cancer Vaccine Launch Pad.
What does the study involve?
Participants wishing to take part in the NHS Cancer Vaccine Launch Pad will be asked to sign a consent form allowing access to information about them and their cancer diagnosis. We will also need to access a sample of unused cancer tissue, that will already have been collected from you, after all routine tests have been done and, in some cases, we will need to collect a blood sample. This will allow us to assess if participants are suitable for the cancer vaccine research trials that the NHS Cancer Vaccine Launch Pad is working with.
Suitable patients will then be referred to the nearest hospital that is running the research trials of a cancer vaccine. The research trials are likely to be at a different NHS hospital so participants will need to travel to these hospitals if they chose to take part and are eligible for the trial.
What are the possible benefits and risks of participating?
Benefits of consenting to join the CVLP include:
- Participants may be able to take part in a research trial and receive cancer vaccine treatment before it is widely available.
- For participants who receive a cancer vaccine treatment, it may reduce the chance of their cancer growing or coming back.
- Participants will be helping medical research to assess the effectiveness of potential treatments.
Possible risks are:
- Not everyone will be suitable to take part in a research trial of a cancer vaccine.
- The research may not benefit everyone that takes part as we are still finding out how effective the treatment might be.
- Many cancer vaccines are new treatments, which means there might be side effects we don't know about yet.
The NHS Cancer Vaccine Launch Pad (CVLP) is funded and sponsored by NHS England. The study is coordinated by the Southampton Clinical Trials Unit. The study is also supported by NIHR.
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The CVLP is a national study open at the following hospitals:
- Maidstone & Tunbridge Wells NHS trust
- University Hospital Southampton NHS Trust
- Lewisham & Greenwich NHS Trust
- Royal Surrey County Hospital NHS Foundation Trust
- University Hospitals Sussex NHS Foundation Trust
- East Sussex Healthcare NHS Trust
- Cambridge University Hospitals NHS Foundation Trust
- Barking Havering and Redbridge University Hospitals NHS Trust
- East Suffolk and North Essex NHS Foundation Trust
- Mid and South Essex NHS Foundation Trust
- Univeristy Hospitals Dorset NHS Foundation Trust
- Buckinghamshire Healthcare NHS Trust
- The Hillingdon Hospitals NHS Foundation Trust
- Oxford University Hospitals NHS Foundation Trust
- Nottingham University Hospitals NHS Trust
- South Warwickshire NHS Foundation Trust
- The Royal Wolverhampton NHS Trust
- Walsall Healthcare NHS Trust
- University Hospitals of North Midlands NHS Trust
- Leeds Teaching Hospitals NHS Trust
- Northern Care Alliance NHS Foundation Trust
- Sheffield Teaching Hospitals NHS Foundation Trust
- University Hospitals Plymouth NHS Trust
- Somerset NHS Foundation Trust
- Royal Devon University Healthcare NHS Foundation Trust
- University Hospitals Bristol and Weston NHS Foundation Trust
- North Bristol NHS Trust
- Royal United Hospitals Bath NHS Foundation Trust
- Gloucestershire Hospitals NHS Foundation Trust
- University Hospitals Morecambe Bay NHS Foundation Trust
- East Lancashire Hospitals NHS Trust
- North Cumbria Integrated Care NHS Foundation Trust
- South Tyneside and Sunderland NHS Foundation Trust
- South Tees Hospitals NHS Foundation Trust
- Northumbria Healthcare NHS Foundation Trust
- North Tees and Hartlepool NHS Foundation Trust
- Harrogate and District NHS Foundation Trust
- Manchester University NHS Foundation Trust
Please note that not all hospitals will be involved in all of the trials supported by CVLP. You can find a list of the hospitals screening for each of the supported trials on the Supported Vaccine Trials page.
Information for research teams
If you are a researcher or part of a research team at a site already taking part in the CVLP study, more information can be found on the CVLP Site Resources page. Or contact us through [email protected].
If you are a researcher or part of a research team at a site not already involved in the CVLP and would like more information on joining, please contact us through [email protected].
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The CVLP is currently supporting the following research trials of cancer vaccines
Colorectal
BNT122-01
Find out more about this vaccine trial on the Be Part of Research webpage.
This study is accessible through the following CVLP sites:
- Maidstone & Tunbridge Wells NHS trust
- University Hospital Southampton NHS Trust
- Lewisham & Greenwich NHS Trust
- Royal Surrey County Hospital NHS Foundation Trust
- University Hospitals Sussex NHS Foundation Trust
- East Sussex Healthcare NHS Trust
- Cambridge University Hospitals NHS Foundation Trust
- Barking Havering and Redbridge University Hospitals NHS Trust
- East Suffolk and North Essex NHS Foundation Trust
- Mid and South Essex NHS Foundation Trust
- Univeristy Hospitals Dorset NHS Foundation Trust
- Buckinghamshire Healthcare NHS Trust
- The Hillingdon Hospitals NHS Foundation Trust
- Oxford University Hospitals NHS Foundation Trust
- Nottingham University Hospitals NHS Trust
- South Warwickshire NHS Foundation Trust
- The Royal Wolverhampton NHS Trust
- Walsall Healthcare NHS Trust
- University Hospitals of North Midlands NHS Trust
- Leeds Teaching Hospitals NHS Trust
- Northern Care Alliance NHS Foundation Trust
- Sheffield Teaching Hospitals NHS Foundation Trust
- University Hospitals Plymouth NHS Trust
- Somerset NHS Foundation Trust
- Royal Devon University Healthcare NHS Foundation Trust
- University Hospitals Bristol and Weston NHS Foundation Trust
- North Bristol NHS Trust
- Royal United Hospitals Bath NHS Foundation Trust
- Gloucestershire Hospitals NHS Foundation Trust
- University Hospitals Morecambe Bay NHS Foundation Trust
- East Lancashire Hospitals NHS Trust
- North Cumbria Integrated Care NHS Foundation Trust
- South Tyneside and Sunderland NHS Foundation Trust
- South Tees Hospitals NHS Foundation Trust
- Northumbria Healthcare NHS Foundation Trust
- North Tees and Hartlepool NHS Foundation Trust
- Harrogate and District NHS Foundation Trust
- Manchester University NHS Foundation Trust
Patients and potential study participants
This page provides information for study participants and patients interested in finding out more information on joining the CVLP.
Read the Participant Information Sheet
Frequently Asked Questions
How do cancer vaccine trials work?
Cancer vaccine trials are being carried out to find out whether cancer vaccines are effective at stopping cancers from returning after normal cancer treatment. This will be in the form of randomised controlled trials. This means that some patients will receive their usual cancer care in the NHS, or in addition, a cancer vaccine.
Do cancer vaccines prevent people from getting cancer?
Cancer vaccines are for people who have had a cancer diagnosed and are going through treatment. Cancer vaccines may reduce the risk of the cancer coming back in the future, but they do not prevent people from getting cancer in the first place.
Why are cancer vaccines not available to everyone who has cancer?
Cancer is different for every person, so there can’t be one cancer vaccine that works for everyone. Different cancers will need to be treated by different vaccines, which is why cancer vaccines are tailored to each person and the type of cancer that they have.
What should I do if I’d like to be considered for a cancer vaccine trial?
Your local doctor will be able to let you know if there are any cancer vaccine clinical trials that you might be eligible for and will talk to you about taking part.
Can I receive other treatments at the same time as the vaccination?
You will not be able to receive other treatment for your cancer while you are receiving treatment with a cancer vaccine. You will be able to receive treatment for any side effects or other conditions you have.
How long will the clinical trials last?
This will be dependent on the cancer vaccine clinical trial that you are taking part in.
What is the age eligibility?
The eligibility will be dependent on each cancer vaccine clinical trial. Please talk to your local hospital team to see if you are eligible for any cancer vaccine trials.
Are there criteria for taking part in the NHS Cancer Vaccine Launch Pad?
Yes, not everyone will be able to take part in the NHS Cancer Vaccine Launch Pad. Your doctor will be able to let you know if there are cancer vaccine clinical trials that you might be eligible for and will ask you if you would like to take part.
Will I be told which hospital is running the cancer vaccine clinical trial?
Before you consent to the cancer vaccine trial, you will be advised of the closest trial hospital to you. You would need to travel to this hospital to take part in the cancer vaccine clinical trial.
Does my cancer treatment transfer to the cancer vaccine trial hospital?
If you choose to take part in the trial and are eligible, you may receive a vaccine at the hospital running the clinical trial. If you choose not to take part or are ineligible, you will continue to have your normal cancer treatment at your local hospital.
Where will my normal cancer treatment take place?
Your normal cancer treatment will take place at your local hospital. Screening for the cancer vaccine trial will take place at the hospital running the clinical trial, as well as the vaccinations if you are eligible for the study.
Will I need to provide a sample of my cancer?
As part of your normal care, you will be having some or all of your cancer removed. If this has already happened, samples from your previous surgery or biopsy will be used. You will not need to undergo an extra procedure to get a tissue sample for the Cancer Vaccine Launch Pad or cancer vaccine trial.
Will I be reimbursed for my travel to the trial site?
There will be reimbursement available to cover transportation, meals and parking fees for yourself and carer when you have to travel to the hospital running the cancer vaccine clinical trial. This is likely to be arranged by the hospital running the cancer vaccine clinical trial but may be arranged through your local hospital depending on the arrangements of the cancer vaccine trial.
Can I take part in other clinical trials other than for cancer vaccines?
Yes, you can take part in other clinical trials if you are eligible. You can ask your local doctor, nurse or healthcare professional if they know or any clinical trials that you may be eligible to join.
The Be Part of Research website, which can also be accessed on the NHS App, has information about clinical trials, what taking part might involve and any trials that may be relevant to you. Once you’ve found a study, you can see all the details including who to contact so you can ask to take part. You can also download, save or print the full study details so you can talk to your doctor, nurse or healthcare professional about it.
For some health conditions, you can also find out about clinical trials from the websites of charities.
If you would like to take part in the CVLP, we recommend you speak to your local hospital team to find out if you may be eligible for recruitment and whether the study is open near you.
This page provides information for researchers and research teams at sites taking part in the CVLP
Downloadable trial documentation for sites taking part in the CVLP.
Videos and information to help sites in the set-up and running of the CVLP.
Press releases, video clips and other external websites
(University of Southampton cannot accept responsibility for external websites)
CVLP patient story - Aug 2024
BBC Inside Health presenter James Gallagher meets Steve, one of the first patients to recieve a cancer vaccine through the NHS Cancer Vaccine Launch Pad, and discusses the technology behind personalised cancer vaccines.
CVLP launch, May 2024
Thousands of cancer patients to trial personalised vaccines
'Ground-breaking' cancer vaccine trial announced.
Southampton Clinical Trials Unit to run ground-breaking NHS cancer vaccine programme.