The NIHR Wellcome Trust Clinical Research Facility at the Southampton General Hospital is taking part in a new study. This study aims to develop better understanding of how to prevent whooping cough.
Whooping cough, also called pertussis, is a bacterial infection of the lungs and airways. It is caused by a bacterium called Bordetella pertussis (B. pertussis). The first symptoms are similar to those of a cold. Intense coughing bouts typically start about a week later. Although a pertussis vaccine is offered to all babies in the UK, the vaccine does not offer lifelong protection.
This study is part of a project that aims to develop a better vaccine against whooping cough. To do this, the team needs to know more about the immune response generated against B. pertussis and what kind of immune response protects against whooping cough. This study is designed to look at those particular questions by inoculating healthy volunteers with nose drops containing B. pertussis, then monitoring their immune response before giving them an antibiotic to clear B. pertussis.
You may be eligible to take part in this study if you are:
- A healthy adult aged 18 to 45 years
- Willing to take a curative antibiotic regimen after inoculation with B. pertussis according to the study protocol
- Willing to be admitted to the NIHR-WTCRF Southampton for 17 days
Participants will be provided compensation up to £3526 for their time, inconvenience and travel.
To find out more please contact: [email protected] or call Tel.+44 (0)23 8120 3853.
Ethics ID: 17/SC/0006
ERGO ID: 24498
