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Research project

Developing immunostimulatory antibodies to deliver agonism without toxicity

Staff

Lead researcher

Professor Aymen Al-Shamkhani

Professor in Immunology

Research interests

  • Cancer Immunotherapy
  • Immunobiology of costimulatory receptors
  • Immunostimulatory antibodies
Connect with Aymen

Email: [email protected]

Other researchers

Professor Jonathan Essex

Professor
Connect with Jonathan

Email: [email protected]

Professor Mark Cragg

Professor in Experimental Cancer Biology

Research interests

  • Antibody biology
  • Antibody engineering
  • Cancer Immunotherapy
Connect with Mark

Email: [email protected]

Professor Stephen Beers

Professor of Immunology & Immunotherapy
Connect with Stephen

Email: [email protected]

Professor Peter Johnson CBE MD FRCP FMedSci

Professor of Medical Oncology
Connect with Peter

Email: [email protected]

Dr Ali Roghanian PhD, FHEA

Associate Professor

Research interests

  • Cancer immunotherapy
  • Monoclonal antibodies
  • Immunoinhibitory receptors
Connect with Ali

Email: [email protected]

Dr Ivo Tews

Associate Professor

Research interests

  • Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
  • Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
  • Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Connect with Ivo

Email: [email protected]

Collaborating research institutes, centres and groups

Molecular and Precision Biosciences

We research how molecular machinery governs cellular life, developing tools to tackle diseases caused when these molecular operations are disrupted.

Research outputs