Research project

Defining the role of ZEB1-dependent epithelial-mesenchymal crosstalk in lung fibrosis

  • Research groups:
  • Lead researchers:
  • Research funder:
    Medical Research Council
  • Status:
    Not active

Project overview

Idiopathic pulmonary fibrosis (IPF) is a life-threatening condition of the lungs where tissue becomes thickened, stiff, and scarred, limiting the amount of oxygen getting into the blood. The aim of this project is to provide effective targeted therapies for sufferers to reduce symptoms of this devastating disease and improve their quality of life as well as to identify biomarkers for IPF patients.

Staff

Lead researchers

Dr Yihua Wang

Associate Professor

Research interests

  • Cell Signalling in Disease
  • Epithelial-Mesenchymal Crosstalk
  • Pulmonary Fibrosis
Connect with Yihua

Collaborating research institutes, centres and groups

Research outputs

Franco Conforti, Robert Ridley, Christopher J Brereton, Aiman Alzetani, Mark Jones, Donna Davies, Paul Skipp, Yihua Wang, Christian Ottensmeier, B. Marshall, Sophie Fletcher, Luca Richeldi & Benjamin Johnson, 2020, Cell Death and Discovery, 6
Type: article
Dian Liu, Ayse Ertay, Charlotte Hill, Yilu Zhou, Juanjuan Li, Yanmei Zou, Hong Qiu, Xianglin Yuan, Robert Ewing, Xin Lu, Hua Xiong & Yihua Wang, 2020, Cell Death and Disease, 11(4)
Type: article
Yuan Yuan, Yilu Zhou, Yali Li, Charlotte Hill, Robert Ewing, Mark Jones, Donna Davies, Zhenglin Jiang & Yihua Wang, 2020, International Journal of Molecular Sciences, 21(4), 1-19
Type: article