Research project

A Lotery MRC Self

Lead researchers:

Professor Andrew Lotery
Other researchers:

Emeritus Professor David Wilson
Research funder:

Medical Research Council
Status:

Not active

Staff

Lead researchers

Professor Andrew Lotery

Professor of Ophthalmology

Research interests

Ocular clinical trials
Age related macular degeneration
Central serous chorioretinopathy

Connect with Andrew

Email: [email protected]

Other researchers

Emeritus Professor David Wilson BA, MB.BS, PhD

Connect with David

Email: [email protected]

Research outputs

Evidence that the Ser192Tyr/Arg402Gln in cis Tyrosinase gene haplotype is a disease-causing allele in oculocutaneous albinism type 1B (OCA1B)

Siying Lin, Aida Sanchez-Bretano, Joseph S Leslie, Katie B Williams, Helena Lee, Nicholas Thomas, Jonathan L Callaway, James Deline, J. Arjuna Ratnayaka, Diana Baralle, Melanie A Schmitt, Chelsea S Norman, Sheri Hammond, V. Gaurav Harlalka, Sarah Ennis, Harold E. Cross, Olivia Wenger, Andrew H. Crosby, Emma L. Baple & James Self, 2022, npj Genomic Medicine, 7(1), 2

DOI: 10.1038/s41525-021-00275-9

Type: article

Novel therapeutics in nystagmus- what has the genetics taught us so far?

James Self & Helena Lee, 2021, Therapeutic Advances in Rare Disease (TAIRD)

DOI: 10.1177/2633004021998714

Type: article

Supranuclear eye movements and nystagmus in children

D. Osborne, M. Theodorou, H. Lee, M. Ranger, M. Hedley-Lewis, F. Shawkat, C.M. Harris & J.E. Self, 2019, Eye, 33(2), 261-273

DOI: 10.1038/s41433-018-0216-y

Type: article

Mutations in TYR and OCA2 associated with oculocutaneous albinism in Pakistani families

Muhammad Waqar Arshad, Gaurav V. Harlalka, Siying Lin, Ilaria D'Atri, Sarmad Mehmood, Muhammad Shakil, Muhammad Jawad Hassan, Barry A. Chioza, Jay E. Self, Sarah Ennis, Luke O'Gorman, Chelsea Norman, Tahir Aman, Shaheer Sabz Ali, Haiba Kaul, Emma L. Baple, Andrew H. Crosby, Muhammad Ikram Ullah & Muhammad Imran Shabbir, 2018, Meta Gene, 17, 48-55

DOI: 10.1016/j.mgene.2018.03.007

Type: article

Identification of a functionally significant tri-allelic genotype in the Tyrosinase gene (TYR) causing hypomorphic oculocutaneous albinism (OCA1B)

Chelsea S. Norman, Luke O'Gorman, Jane Gibson, Reuben J. Pengelly, Diana Baralle, J. Arjuna Ratnayaka, Helen Griffiths, Matthew Rose-Zerilli, Megan Ranger, David Bunyan, Helena Lee, Rhiannon Page, Tutte Newall, Fatima Shawkat, Christopher Mattocks, Daniel Ward, Sarah Ennis & Jay E. Self, 2017, Scientific Reports, 7, 1-9

DOI: 10.1038/s41598-017-04401-5

Type: article