Emeritus Professor Graham Packham

Cancer Research UK Southampton Centre - Non-Clinical Training Award

Sponsor: Cancer Research UK

Researchers:

Professor Diana Eccles ,

Professor Tim Underwood ,

Professor Stephen Beers ,

Doctor Jeremy Blaydes ,

Professor Edd James ,

Professor John Primrose ,

Professor Alex Mirnezami ,

Professor Aymen Al-Shamkhani ,

Professor Simon Crabb ,

Early Cancer Research Initiative Network on MBL and MGUS models (ECRIN-M3)

Professor Juliet Gray ,

Doctor Ellen Copson ,

Professor Gareth Thomas ,

Professor Sean Lim

Sponsor: Cancer Research UK

Researchers:

Professor James Batchelor ,

G Packham. LLR. 11053. Oxidative stress in chronic lymphocytic leukaemia

Mrs Helen Parker ,

Doctor Dean Bryant ,

Mr Ben Sale

Sponsor: Cancer Research UK

Completed projects

Researchers:

Using Chemical Probes to investigate redox regulation of Angiogenesis

Sponsor: Blood Cancer UK

Researchers:

Precision Cancer Medicine: Forefront Technologies at the Clinical Interface Meeting at the University of Southampton, 14th September 2017

Sponsor: Gerald Kerkut Charitable Trust

Researchers:

Packham, Bloodwise/KKLF, B‐cell receptor signalling in B –cell malignancies: identifying strategies for optimal therapeutic intervention based on common and distinct responses

Professor Hywel Morgan ,

Professor Peter Smith

Sponsor: Cancer Research UK

Researchers:

Professor Jon Strefford

Sponsor: Blood Cancer UK

CRUK pilot project grant

Researchers:

Smith C1641/A5745 prim c cell lymphomh

Sponsor: Cancer Research UK

Researchers:

KKL408: Biological significance and therapeutic targeting of the B-cell receptor-induced unfolded protein response in Chronic Lymphocytic Leukaemia

Sponsor: Cancer Research UK

Researchers:

G Packham AICR 13-0267 Lectin Mediated B cell receptor

Sponsor: The Kay Kendall Leukaemia Fund

Researchers:

B-cell receptor signalling in B-cell malignancies: Identifying strategies for optimal therapeutic intervention based on common and distinct responses

Sponsor: Worldwide Cancer Research

Researchers:

Packham LLR 14045 Gordon Pillar PhD Studentship Opposing kinase activation in B-cell malignancies

Sponsor: Cancer Research UK

Researchers:

Prof G Packham - LRF - 07083: Cutaneous T Cell Lymphoma and Histone Deacetylase Inhibitors

Sponsor: Blood Cancer UK

Researchers:

Sponsor: Blood Cancer UK

G Packham C2750/A4883

Researchers:

Sponsor: Cancer Research UK

G Packham C2750/A2740

Researchers:

Packham. LLR. 11023. MYC potential target for therapeutic attack in chronic leukaemia

Sponsor: Cancer Research UK

Researchers:

G Packham CLL B-cell receptor and CXCR4 cross-talk

Sponsor: Blood Cancer UK

Researchers:

Packham - CRUK - C15966/A15968 - Personalised Epigenetic Therapy for Follicular Lymphoma (QMUL)

Sponsor: Global Research Foundation

Researchers:

A Ganesan G Packham C2750/A8016

Sponsor: Cancer Research UK

Researchers:

Aquinox Screening Project NXT-POC-01 MTA2

Sponsor: Cancer Research UK

Researchers:

Packham. LLR. 13036. Effects of B-Cell receptor stimulation in chronic lymphocytic leukaemia

Sponsor: Aquinox Pharmaceuticals (Canada) Inc

Researchers:

P Glynne-Jones - High-Throughput Optical Blood Imaging for the Detection of Rare Cells using Ultrasonic Particle Alignment

Sponsor: Blood Cancer UK

Researchers:

Doctor Peter Glynne-Jones

Forconi LLR 14037 The influence of altered genetics on B-cell receptor levels and function in CLL

Sponsor: EPSRC

Researchers:

Steele LLR 12044 autophagy in chronic lymphocytic leukaemia

Sponsor: Blood Cancer UK

Researchers:

Cragg- Gilead Services Inc - Combination of PI3K inhibitors and anti-CD20 mAbs

Sponsor: Blood Cancer UK

Researchers:

Prof Stevenson - Tenovus SA59

Sponsor: Gilead Sciences Inc

Researchers:

S Crabb - CRUK - C9317/A20783 - Therapeutic inhibition of the histone demethylase LSD1 to attenuate androgen receptor signalling in prostate cancer that is resistant to new generation AR antagonists

Sponsor: Tenovus

Researchers:

Professor Simon Crabb

Packham, Bloodwise/KKLF, B‐cell receptor signalling in B –cell malignancies: identifying strategies for optimal therapeutic intervention based on common and distinct responses

Sponsor: Cancer Research UK

Researchers:

J Strefford. LLR. 11052. Characterization of causative loci

Sponsor: The Kay Kendall Leukaemia Fund

Researchers:

Professor Jon Strefford

Cancer Research UK Southampton Centre - Clinical Training Award

Sponsor: Blood Cancer UK

Researchers:

Professor Diana Eccles ,

Professor Stephen Beers ,

Professor Tim Underwood ,

Doctor Jeremy Blaydes ,

Professor Edd James ,

Professor John Primrose ,

Professor Alex Mirnezami ,

Professor Aymen Al-Shamkhani ,

Professor Simon Crabb ,

Steele LLR 14040 B cell receptor signalling is modified by IL-4 in chronic lymphocytic leukaemia CLL

Professor Juliet Gray ,

Doctor Ellen Copson ,

Professor Gareth Thomas ,

Professor Sean Lim

Sponsor: Cancer Research UK

Researchers:

Hayden Wessex R05 LSD1 Inhibitors for prostate cancer

Sponsor: Blood Cancer UK

Researchers:

Professor Simon Crabb

Cragg Kay Kendall Trust Resistance of CLL to anti-CD20 mAbs

Sponsor: Wessex Medical Research

Researchers:

Cancer Research UK Southampton Centre

Sponsor: The Kay Kendall Leukaemia Fund

Researchers:

Professor Diana Eccles ,

Professor Tim Underwood ,

Professor Stephen Beers ,

Doctor Jeremy Blaydes ,

Professor Edd James ,

Professor John Primrose ,

Professor Alex Mirnezami ,

Professor Aymen Al-Shamkhani ,

Professor Simon Crabb ,

Professor Juliet Gray ,

Doctor Ellen Copson ,

Professor Gareth Thomas ,

Professor Sean Lim

Sponsor: Cancer Research UK

Dr A. Steele: CLL

Researchers:

Cragg - KKLF - KKL981 - Overcoming tissue-mediated resistance of CLL to anti-CD20 monoclonal antibody therapy.

Sponsor: Blood Cancer UK

Researchers:

Sponsor: The Kay Kendall Leukaemia Fund

Dr Strefford ref 06021

Researchers:

Professor Jon Strefford

S Crabb PCUK Therapeutic inhibition of the histone demethylase

Sponsor: Blood Cancer UK

Researchers:

Professor Simon Crabb

Susceptibility of Patient derived xenograph (PDX) models of Leukemia/lymphoma to cerdulatinib alone or in combination with venetoclax or rituximab

Sponsor: Prostate Cancer UK

Researchers:

Exploiting surface Ig glycans of germinal centre lymphomas for diagnosis, prognosis and therapy

Sponsor: Portola Pharmaceuticals

Researchers:

Professor Peter Johnson ,

Cutress 2011NovPR39 BAG1 as a therapeutic target in HER2

Sponsor: Blood Cancer UK

Researchers:

Professor Ramsey Cutress

Steele - KKLF - Investigating the impact of interleukin-4 in CLL Biology

Sponsor: Breast Cancer Now

Researchers:

Prof C Harrison LRF grant 07011

Sponsor: The Kay Kendall Leukaemia Fund

Researchers:

P Townsend: Proteomic screening for early detection in breast and colorectal cancer

Sponsor: Blood Cancer UK

Researchers: