southampton

Research

Research groups

Member of:

Centre for Human Development, Stem Cells and Regeneration

Research projects

Active projects

B-cell receptor signalling in B-cell malignancies: Identifying strategies for optimal therapeutic intervention based on common and distinct responses

Researchers:

Sponsor: Cancer Research UK

CRUK Clinical Academic Training Programme Award

Researchers:

Sponsor: Cancer Research UK

Cancer Research UK Southampton Centre - Non-Clinical Training Award

Researchers:

Sponsor: Cancer Research UK

Early Cancer Research Initiative Network on MBL and MGUS models (ECRIN-M3)

Researchers:

Sponsor: Cancer Research UK

Completed projects

G Packham. LLR. 11053. Oxidative stress in chronic lymphocytic leukaemia

Researchers:

Sponsor: Blood Cancer UK

Using Chemical Probes to investigate redox regulation of Angiogenesis

Researchers:

Sponsor: Gerald Kerkut Charitable Trust

Precision Cancer Medicine: Forefront Technologies at the Clinical Interface Meeting at the University of Southampton, 14th September 2017

Researchers:

Sponsor: Cancer Research UK

Packham, Bloodwise/KKLF, B‐cell receptor signalling in B –cell malignancies: identifying strategies for optimal therapeutic intervention based on common and distinct responses

Researchers:

Sponsor: Blood Cancer UK

CRUK pilot project grant

Researchers:

Sponsor: Cancer Research UK

Smith C1641/A5745 prim c cell lymphomh

Researchers:

Sponsor: Cancer Research UK

KKL408: Biological significance and therapeutic targeting of the B-cell receptor-induced unfolded protein response in Chronic Lymphocytic Leukaemia

Researchers:

Sponsor: The Kay Kendall Leukaemia Fund

G Packham AICR 13-0267 Lectin Mediated B cell receptor

Researchers:

Sponsor: Worldwide Cancer Research

Packham LLR 14045 Gordon Pillar PhD Studentship Opposing kinase activation in B-cell malignancies

Researchers:

Sponsor: Blood Cancer UK

Prof G Packham - LRF - 07083: Cutaneous T Cell Lymphoma and Histone Deacetylase Inhibitors

Researchers:

Sponsor: Blood Cancer UK

G Packham C2750/A4883

Researchers:

Sponsor: Cancer Research UK

G Packham C2750/A2740

Researchers:

Sponsor: Cancer Research UK

Packham. LLR. 11023. MYC potential target for therapeutic attack in chronic leukaemia

Researchers:

Sponsor: Blood Cancer UK

G Packham CLL B-cell receptor and CXCR4 cross-talk

Researchers:

Sponsor: Global Research Foundation

Packham - CRUK - C15966/A15968 - Personalised Epigenetic Therapy for Follicular Lymphoma (QMUL)

Researchers:

Sponsor: Cancer Research UK

A Ganesan G Packham C2750/A8016

Researchers:

Sponsor: Cancer Research UK

Aquinox Screening Project NXT-POC-01 MTA2

Researchers:

Sponsor: Aquinox Pharmaceuticals (Canada) Inc

Packham. LLR. 13036. Effects of B-Cell receptor stimulation in chronic lymphocytic leukaemia

Researchers:

Sponsor: Blood Cancer UK

P Glynne-Jones - High-Throughput Optical Blood Imaging for the Detection of Rare Cells using Ultrasonic Particle Alignment

Researchers:

Sponsor: EPSRC

Forconi LLR 14037 The influence of altered genetics on B-cell receptor levels and function in CLL

Researchers:

Sponsor: Blood Cancer UK

Steele LLR 12044 autophagy in chronic lymphocytic leukaemia

Researchers:

Sponsor: Blood Cancer UK

Cragg- Gilead Services Inc - Combination of PI3K inhibitors and anti-CD20 mAbs

Researchers:

Sponsor: Gilead Sciences Inc

Prof Stevenson - Tenovus SA59

Researchers:

Sponsor: Tenovus

S Crabb - CRUK - C9317/A20783 - Therapeutic inhibition of the histone demethylase LSD1 to attenuate androgen receptor signalling in prostate cancer that is resistant to new generation AR antagonists

Researchers:

Sponsor: Cancer Research UK

Packham, Bloodwise/KKLF, B‐cell receptor signalling in B –cell malignancies: identifying strategies for optimal therapeutic intervention based on common and distinct responses

Researchers:

Sponsor: The Kay Kendall Leukaemia Fund

J Strefford. LLR. 11052. Characterization of causative loci

Researchers:

Sponsor: Blood Cancer UK

Cancer Research UK Southampton Centre - Clinical Training Award

Researchers:

Sponsor: Cancer Research UK

Steele LLR 14040 B cell receptor signalling is modified by IL-4 in chronic lymphocytic leukaemia CLL

Researchers:

Sponsor: Blood Cancer UK

Hayden Wessex R05 LSD1 Inhibitors for prostate cancer

Researchers:

Sponsor: Wessex Medical Research

Cragg Kay Kendall Trust Resistance of CLL to anti-CD20 mAbs

Researchers:

Sponsor: The Kay Kendall Leukaemia Fund

Cancer Research UK Southampton Centre

Researchers:

Sponsor: Cancer Research UK

Dr A. Steele: CLL

Researchers:

Sponsor: Blood Cancer UK

Cragg - KKLF - KKL981 - Overcoming tissue-mediated resistance of CLL to anti-CD20 monoclonal antibody therapy.

Researchers:

Sponsor: The Kay Kendall Leukaemia Fund

Dr Strefford ref 06021

Researchers:

Sponsor: Blood Cancer UK

S Crabb PCUK Therapeutic inhibition of the histone demethylase

Researchers:

Sponsor: Prostate Cancer UK

Susceptibility of Patient derived xenograph (PDX) models of Leukemia/lymphoma to cerdulatinib alone or in combination with venetoclax or rituximab

Researchers:

Sponsor: Portola Pharmaceuticals

Exploiting surface Ig glycans of germinal centre lymphomas for diagnosis, prognosis and therapy

Researchers:

Sponsor: Blood Cancer UK

Cutress 2011NovPR39 BAG1 as a therapeutic target in HER2

Researchers:

Sponsor: Breast Cancer Now

Steele - KKLF - Investigating the impact of interleukin-4 in CLL Biology

Researchers:

Sponsor: The Kay Kendall Leukaemia Fund

Prof C Harrison LRF grant 07011

Researchers:

Sponsor: Blood Cancer UK

P Townsend: Proteomic screening for early detection in breast and colorectal cancer

Researchers:

Sponsor: Wessex Medical Research

Emeritus Professor Graham Packham

Connect with Graham

Research

Research groups

Research projects

Active projects

Completed projects

Publications