Research group

Interdisciplinary Musculoskeletal Health

4 Stained femur cross sections

The University hosts a substantial interdisciplinary community of researchers working to transform musculoskeletal health across the life course.

About

With expertise in regenerative medicine, physiology, engineering, orthopaedics, prosthetics and orthotics, rehabilitation and assistive technologies, epidemiology and clinical trial design, we aim to improve lives by delivering improved treatments, increasing the speed to market of musculoskeletal-focused technology and training the next generation of scientists and engineers. 

The population across the globe is living longer, which brings a number of healthcare challenges, especially in musculoskeletal health. The burden of age-related disease and injury is rising rapidly, having a detrimental impact on people’s quality of life and increasing the costs of healthcare provision. Loss of muscle mass and function is the leading reason for loss of independence in later life, and causes impaired mobility, falls, fractures, physical disability, increased insulin resistance and associated co-morbidities, and mortality. The number of hip fractures is expected to rise to 6.3 million by 2050 and the number of diabetic lower limb amputations has now risen to 7,000 per year in the UK and over 70,000 in the USA. 

The University is working to meet these challenges by creating networks of experts working in interdisciplinary musculoskeletal health research to develop new technologies, interventions and practices that will have a positive effect on people’s lives:

  • FortisNet is an interdisciplinary research network of clinical, academic and industrial partners that aims to develop products and services to transform musculoskeletal health. Launched in 2016, we have fostered over 50 new collaborations with other universities from across the UK, the NHS and industry. We have developed courses with national partners to help innovators understand how to bring medical technologies to market, and through investment in interdisciplinary studentships we are working to dissolve discipline boundaries, to train a new generation of life scientists and engineers for the benefit of society.
  • MyAge (Muscle resilience across the life course: from cells to society) is one of eleven UK Ageing Networks, funded by the Biotechnology and Biological Sciences Research Council and Medical Research Council. Led by the Institute for Life Sciences, together with partners from Birmingham, Nottingham and Imperial, the network will guide the future of muscle resilience research through roadmap development and interdisciplinary collaboration.

Research highlights

Preventing the transmission of non-communicable disease risk between generations

Research from the Developmental Origins of Health and Disease Centre demonstrates how the diet and lifestyle choices of prospective parents and pregnant mothers can affect the long-term health of their children.

Using nanoclay gel to regrow, repair and replace damaged cells

Southampton researchers have developed an innovative medical clay that can be used to apply regenerative medicine to patients with musculoskeletal conditions.

People, projects and publications

People

Professor Tomas Polcar

Professor of Materials Sci and Tribology
Connect with Tomas

Professor Tracey Newman

Professor

Research interests

  • The demographic of populations worldwide is changing. People are living longer but with more years with affected by disability in the last two decades of life. The societal and economic consequences of this change are not being well managed. There is a lag in the development of health interventions and a need for rapid learning for future health and infrastructure planning. Typically, people in poorer economic situations are disproportionately affected by disability in later life.
  • Hearing loss and dementia: I lead multidisciplinary research focussed on hearing loss, the use of cochlear implants to restore hearing in otherwise deaf people and the interaction between hearing loss and dementia.
  • My focus is understanding cellular mechanisms in these conditions and also how the learning and methodologies used to investigate this can be applied across discipline boundaries. I am driving the implementation of data science methodologies for improved management of people who hear with cochlear implants and for the identification of early indicators of cognitive decline. I am championing the engagement of patients in research and as ambassadors to increase awareness of healthcare interventions amongst hard to reach and marginalised communities.

Accepting applications from PhD students

Connect with Tracey

Dr Tracy Melvin

Associate Professor
Connect with Tracy

Dr Valentina Cardo

Associate Professor

Research interests

  • Valentina's research interests include:
  • The relationship between citizenship and identity;
  • Political representation;

Accepting applications from PhD students

Connect with Valentina

Dr Valerie Brandt

Associate Professor
Connect with Valerie

Dr Veronica Zamora-Gutierrez

Lecturer in Ecology

Research interests

  • Biodiversity
  • Global Change and Conservation
  • Ecosystem Services

Accepting applications from PhD students

Connect with Veronica

Professor Vincent O'connor

Professor of Neurochemistry

Research interests

  • Molecular mechanism of synaptic function and dysfunction
  • Synaptic degeneration
  • Genetic models of synaptic and neuronal dysfunction

Accepting applications from PhD students

Connect with Vincent

Professor Vladimir Jiranek

Professor

Research interests

  • Microbiology of beverage fermentations 
  • Cell-cell interations and filamentous/invasive growth in yeast
  • How has yeast evolved to survive in nature and interact with insects 

Accepting applications from PhD students

Connect with Vladimir

Dr William King

Lecturer in Plant-Microbe Interactions

Research interests

  • Root microbiome
  • Microbial interactions
  • Microbiome manipulation

Accepting applications from PhD students

Connect with William

Dr Xiaohao Cai

Lecturer in Computer Science

Research interests

  • Image/signal/data processing
  • Computer vision
  • Machine learning

Accepting applications from PhD students

Connect with Xiaohao

Related research institutes, centres and groups

Related research institutes, centres and groups

Connect with us

We welcome new members. To join, or find out more about FortisNet or MyAge, please email the Institute for Life Sciences team.