Research project

Dr H M Haitchi ADAM33 gene and environmental interactions in developing lungs and their involvement in the early life origin of asthma

Staff

Lead researchers

Professor Hans Michael Haitchi MD, MMed(INT), PhD, PD, MRCP(London), FHEA, PGcert

Professor

Research interests

  • Study of the asthma susceptibility gene A Disintegrin and Metalloprotease 33 (ADAM33) in early life and adult asthma and other chronic lung diseases.
  • Development of novel Anti-ADAM33 agents as potential disease modifying asthma therapy.
  • Multiomic study of the influence of the maternal environment (e.g. allergic asthma, obesity) during pregnancy on ADAM33 and other mediators and the early origin of lung disease in the Maternal Environment in Pregnancy (MEP) cohort.
Connect with Hans Michael

Research outputs

Christopher L. Grainge, Valdeep Dulay, Jonathan Ward, David Sammut, Elizabeth Davies, Benjamin Green, Laurie C.K. Lau, Laura Cottey, Hans-Michael Haitchi, Donna E. Davies & Peter H. Howarth, 2012, Respirology, 17(7), 1094-1100
Type: article
T.R. Korfhagen, J. Kitzmiller, G. Chen, A. Sridharan, H.M. Haitchi, R.S. Hegde, S. Divanovic, C.L. Karp & J.A. Whitsett, 2012, Proceedings of the National Academy of Sciences, 109(41), 16630-16635
Type: article
Youwen Yang, James Wicks, Hans Michael Haitchi, Robert M. Powell, Wiparat Manuyakorn, Peter H. Howarth, Stephen T. Holgate & Donna E. Davies, 2012, American Journal of Respiratory Cell and Molecular Biology, 46(5), 633-640
Type: article
Elizabeth R. Davies, Hans Michael Haitchi, Thomas H. Thatcher, Patricia J. Sime, R. Matthew Kottmann, Arasu Ganesan, Graham Packham, Katherine M.A. O'Reilly & Donna E. Davies, 2012, American Journal of Respiratory Cell and Molecular Biology, 46(5), 687-694
Type: article