Research project

Cost-effective multi-cancer early detection by measuring patient plasma amino acid cross sections with the Enlighten test

Staff

Professor of Haematological Oncology

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Professor of Exp'tl Cancer Therapeutics

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Sn Medical Statistician(Scientific Lead)

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Director SCTU & Prof of Clinical Trials

Gareth Griffiths is Professor of Clinical Trials and directs our Southampton Clinical Trials Unit. He works with clinicians, research groups and other scientists in the development of important clinical trials and other well-designed studies that aim to improve the treatment of a range of cancers and other diseases, and early diagnosis of cancer.
His works spans the different phases of clinical trials, from small dose finding and safety studies involving a handful of patients to larger trials of hundreds of patients looking at whether the treatments are better than the current standard treatments. His early diagnosis studies include thousands of patients looking at new ways to detect cancer early. Ultimately, these studies could help change the way that patients are treated for the better, by creating the evidence so as the new treatments becomes the standard of care for future patients treated in the NHS.
Phase I-III clinical trials

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Director of SHTAC

Joanne has research interests in health economic evaluation and decision modelling.
She has worked on a wide range of applied cost-effectiveness studies, including:
a review of newborn screening for inborn errors of metabolism;trials of diagnosis, patient education, structured decision-making and therapeutic interventions for arthritis and back pain;evaluations of diagnostic tests, preventive treatment and contact tracing for tuberculosis;a model of geographic allocation of resources for control of Chagas disease in Central America; andanalyses relating to the prevention and treatment of cardiovascular diseases. Her methodological contributions include an MRC funded project on whole pathway modelling for NICE clinical guidelines and an economic perspective on test evaluation. She has also contributed to health outcome and quality of life studies.

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Email: [email protected]