About the project
No specific therapy exists, and surfactant loss worsens outcomes, with 30-50% mortality. Oxygen therapy is crucial but excessive administration can damage tissues. Our study proposes on-chip spectroscopy for rapid in-vivo surfactant analysis, aiding precise treatments and prevention across all ages.
This PhD project is focused on transforming respiratory care at the bedside to develop a user-friendly, palmtop spectrometer that brings rapid bedside biomarker diagnosis within easy reach for clinicians. Building on our success in mid-infrared spectroscopy and machine learning, our team is creating a practical point-of-care device.
Utilizing disposable enhanced spectroscopic chips, this project aims to analyse in-vivo surfactant metabolism swiftly. By doing so, clinicians can make informed decisions, stratify patients, and prescribe targeted therapies promptly.