southampton

About

Diana Eccles graduated in Medicine from Manchester University in 1983, her clinical training is in general medicine, oncology and clinical genetics and she has worked and trained in Manchester, Edinburgh and Southampton. Her research background is in molecular genetics and genetic epidemiology, her doctoral thesis investigated the molecular genetics of ovarian cancer working in the MRC Human Genetics Unit in Edinburgh, she was awarded her MD in 1992. Previous roles at UoS include Director of the Southampton Clinical Trials Unit (2009-2014) and Head of Cancer Sciences (2015-2018). She contributes to national and international scientific evaluations and peer review including currently the UKRI REF evaluation panel (Main panel A, SP1), MRC CARP (chair) and Research Council of Norway Centres of Excellence panel. Her research focuses on genetic predispostion to cancer and management of hereditary breast cancer She is CI of the UK Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (POSH study) and Co-CI of CanGene-CanVar CRUK Catalyst programme (2019-2024) to improve the interpretation and clinical translation of genetic variants in cancer predisposition genes.

Publications

333 publications

Page 15 of 34

Common genetic variation in cellular transport genes and epithelial ovarian cancer (EOC) risk

Irina U. Agoulnik, Ganna Chornokur, Hui-Yi Lin, Jonathan P. Tyrer, Kate Lawrenson, Joe Dennis, Ernest K. Amankwah, Xiaotao Qu, Ya-Yu Tsai, Heather S.L. Jim, Zhihua Chen, Ann Y. Chen, Jennifer Permuth-Wey, Katja K.H. Aben, Hoda Anton-Culver, Natalia Antonenkova, Fiona Bruinsma, Elisa V. Bandera, Yukie T. Bean, Matthias W. Beckmann, Maria Bisogna, Line Bjorge, Natalia Bogdanova, Louise A. Brinton, Angela Brooks-Wilson, Clareann H. Bunker, Ralf Butzow, Ian G. Campbell, Karen Carty, Jenny Chang-Claude, Linda S. Cook, Daniel W. Cramer, Julie M. Cunningham, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Andreas du Bois, Evelyn Despierre, Ed Dicks, Jennifer A. Doherty, Thilo Dörk, Matthias Dürst, Douglas F. Easton, Diana M. Eccles, Robert P. Edwards, Arif B. Ekici, Peter A. Fasching, Brooke L. Fridley, Yu-Tang Gao, Aleksandra Gentry-Maharaj, Graham G. Giles, Rosalind Glasspool, Marc T. Goodman, Jacek Gronwald, Patricia Harrington, Philipp Harter, Alexander Hein, Florian Heitz, Michelle A. T. Hildebrandt, Peter Hillemanns, Claus K. Hogdall, Estrid Hogdall, Satoyo Hosono, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Beth Y. Karlan, Linda E. Kelemen, Mellissa Kellar, Lambertus A. Kiemeney, Camilla Krakstad, Susanne K. Kjaer, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D. Le, Alice W. Lee, Shashi Lele, Arto Leminen, Jenny Lester, Douglas A. Levine, Dong Liang, Boon Kiong Lim, Jolanta Lissowska, Karen Lu, Jan Lubinski, Lene Lundvall, Leon F. A. G. Massuger, Keitaro Matsuo, Valerie McGuire, John R. McLaughlin, Iain McNeish, Usha Menon, Roger L. Milne, Francesmary Modugno, Kirsten B. Moysich, Roberta B. Ness, Heli Nevanlinna, Ursula Eilber, Kunle Odunsi, Sara H. Olson, Irene Orlow, Sandra Orsulic, Rachel Palmieri Weber, James Paul, Celeste L. Pearce, Tanja Pejovic, Liisa M. Pelttari, Malcolm C. Pike, Elizabeth M. Poole, Harvey A. Risch, Barry Rosen, Mary Anne Rossing, Joseph H. Rothstein, Anja Rudolph, Ingo B. Runnebaum, Iwona K. Rzepecka, Helga B. Salvesen, Eva Schernhammer, Ira Schwaab, Xiao-Ou Shu, Yurii B. Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C. Southey, Beata Spiewankiewicz, Lara Sucheston, Soo-Hwang Teo, Kathryn L. Terry, Pamela J. Thompson, Lotte Thomsen, Ingvild L. Tangen, Shelley S. Tworoger, Anne M. van Altena, Robert A. Vierkant, Ignace Vergote, Christine S. Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S. Whittemore, Kristine G. Wicklund, Lynne R. Wilkens, Anna H. Wu, Xifeng Wu, Yin-Ling Woo, Hannah Yang, Wei Zheng, Argyrios Ziogas, Hanis N. Hasmad, Andrew Berchuck, Edwin S. Iversen, Joellen M. Schildkraut, Susan J. Ramus, Ellen L. Goode, Alvaro N. A. Monteiro, Simon A. Gayther, Steven A. Narod, Paul D. P. Pharoah, Thomas A. Sellers & Catherine M. Phelan, 2015, PLoS ONE, 10(6), e0128106-[17pp]

DOI: 10.1371/journal.pone.0128106

Type: article

Polymorphism at 19q13.41 predicts breast cancer survival specifically after endocrine therapy

S. Khan, R. Fagerholm, S. Rafiq, W. Tapper, K. Aittomaki, J. Liu, C. Blomqvist, D. Eccles & H. Nevanlinna, 2015, Clinical Cancer Research, 1-11

DOI: 10.1158/1078-0432.CCR-15-0296

Type: article

Crowdsourcing the general public for large scale molecular pathology studies in cancer

Francisco J. Candido dos Reis, Stuart Lynn, H. Raza Ali, Diana Eccles, Andrew Hanby, Elena Provenzano, Carlos Caldas, William J. Howat, Leigh-Anne McDuffus, Bin Liu, Frances Daley, Penny Coulson, Rupesh J. Vyas, Leslie M. Harris, Joanna M. Owens, Amy F.M. Carton, Janette P. McQuillan, Andy M. Paterson, Zohra Hirji, Sarah K. Christie, Amber R. Holmes, Marjanka K. Schmidt, Montserrat Garcia-Closas, Douglas F. Easton, Manjeet K. Bolla, Qin Wang, Javier Benitez, Roger L. Milne, Arto Mannermaa, Fergus Couch, Peter Devilee, Robert A.E.M. Tollenaar, Caroline Seynaeve, Angela Cox, Simon S. Cross, Fiona M. Blows, Joyce Sanders, Renate de Groot, Jonine Figueroa, Mark Sherman, Maartje Hooning, Hermann Brenner, Bernd Holleczek, Christa Stegmaier, Chris Lintott & Paul D.P. Pharoah, 2015, EBioMedicine, 1-22

DOI: 10.1016/j.ebiom.2015.05.009

Type: article

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer

Antoinette Hollestelle, Frederieke H. van der Baan, Andrew Berchuck, Sharon E. Johnatty, Katja K. Aben, Bjarni A. Agnarsson, Kristiina Aittomäki, Elisa Alducci, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Antonis C. Antoniou, Carmel Apicella, Volker Arndt, Norbert Arnold, Banu K. Arun, Brita Arver, Alan Ashworth, Laura Baglietto, Rosemary Balleine, Elisa V. Bandera, Daniel Barrowdale, Yukie T. Bean, Lars Beckmann, Matthias W. Beckmann, Javier Benitez, Andreas Berger, Raanan Berger, Benoit Beuselinck, Maria Bisogna, Line Bjorge, Carl Blomqvist, Natalia V. Bogdanova, Anders Bojesen, Stig E. Bojesen, Manjeet K. Bolla, Bernardo Bonanni, Judith S. Brand, Hiltrud Brauch, Hermann Brenner, Louise Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Joan Brunet, Thomas Brüning, Agnieszka Budzilowska, Clareann H. Bunker, Barbara Burwinkel, Ralf Butzow, Saundra S. Buys, Maria A. Caligo, Ian Campbell, Jonathan Carter, Jenny Chang-Claude, Stephen J. Chanock, Kathleen B.M. Claes, J. Margriet Collée, Linda S. Cook, Fergus J. Couch, Angela Cox, Daniel Cramer, Simon S. Cross, Julie M. Cunningham, Cezary Cybulski, Kamila Czene, Francesca Damiola, Agnieszka Dansonka-Mieszkowska, Hatef Darabi, Miguel de la Hoya, Anna deFazio, Joseph Dennis, Peter Devilee, Ed M. Dicks, Orland Diez, Jennifer A. Doherty, Susan M. Domchek, Cecilia M. Dorfling, Thilo Dörk, Isabel Dos Santos Silva, Andreas du Bois, Martine Dumont, Alison M. Dunning, Mercedes Duran, Douglas F. Easton, Diana Eccles, Robert P. Edwards, Hans Ehrencrona, Bent Ejlertsen, Arif B. Ekici, Steve D. Ellis, Christoph Engel, Mikael Eriksson, Peter A. Fasching, Lidia Feliubadalo, Jonine Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Annette Fontaine, Stefano Fortuzzi, Florentia Fostira, Brooke L. Fridley, Tara Friebel, Eitan Friedman, Grace Friel, Debra Frost, Judy Garber, Montserrat García-Closas, Simon A. Gayther, Aleksandra Gentry-Maharaj, Anne-Marie Gerdes, Graham G. Giles, Rosalind Glasspool, Gord Glendon, Andrew K. Godwin, Marc T. Goodman, Martin Gore, Mark H. Greene, Mervi Grip, Jacek Gronwald, Daphne Gschwantler Kaulich, Pascal Guénel, Starr R. Guzman, Lothar Haeberle, Christopher A. Haiman, Per Hall, Sandra L. Halverson, Ute Hamann, Thomas V.O. Hansen, Philipp Harter, Jaana M. Hartikainen, Sue Healey, Alexander Hein, Florian Heitz, Brian E. Henderson, Josef Herzog, Michelle A. T Hildebrandt, Claus K. Høgdall, Estrid Høgdall, Frans B.L. Hogervorst, John L. Hopper, Keith Humphreys, Tomasz Huzarski, Evgeny N. Imyanitov, Claudine Isaacs, Anna Jakubowska, Ramunas Janavicius, Katarzyna Jaworska, Allan Jensen, Uffe Birk Jensen, Nichola Johnson, Arja Jukkola-Vuorinen, Maria Kabisch, Beth Y. Karlan, Vesa Kataja, Noah Kauff, Linda E. Kelemen, Michael J. Kerin, Lambertus A. Kiemeney, Susanne K. Kjaer, Julia A. Knight, Jacoba P. Knol-Bout, Irene Konstantopoulou, Veli-Matti Kosma, Camilla Krakstad, Vessela Kristensen, Karoline B. Kuchenbaecker, Jolanta Kupryjanczyk, Yael Laitman, Diether Lambrechts, Sandrina Lambrechts, Melissa C. Larson, Adriana Lasa, Pierre Laurent-Puig, Conxi Lazaro, Nhu D. Le, Loic Le Marchand, Arto Leminen, Jenny Lester, Douglas A. Levine, Jingmei Li, Dong Liang, Annika Lindblom, Noralane Lindor, Jolanta Lissowska, Jirong Long, Karen H. Lu, Jan Lubinski, Lene Lundvall, Galina Lurie, Phuong L. Mai, Arto Mannermaa, Sara Margolin, Frederique Mariette, Frederik Marme, John W.M. Martens, Leon F.A.G. Massuger, Christine Maugard, Sylvie Mazoyer, Lesley McGuffog, Valerie McGuire, Catriona McLean, Iain McNeish, Alfons Meindl, Florence Menegaux, Primitiva Menéndez, Janusz Menkiszak, Usha Menon, Arjen R. Mensenkamp, Nicola Miller, Roger L. Milne, Francesmary Modugno, Marco Montagna, Kirsten B. Moysich, Heiko Müller, Anna Marie Mulligan, Taru A. Muranen, Steven A. Narod, Katherine L. Nathanson, Roberta B. Ness, Susan L. Neuhausen, Heli Nevanlinna, Patrick Neven, Finn C. Nielsen, Sune F. Nielsen, Børge G. Nordestgaard, Robert L. Nussbaum, Kunle Odunsi, Kenneth Offit, Edith Olah, Olufunmilayo I. Olopade, Janet E. Olson, Sara H. Olson, Jan C. Oosterwijk, Irene Orlow, Nick Orr, Sandra Orsulic, Ana Osorio, Laura Ottini, James Paul, Celeste L. Pearce, Inge Sokilde Pedersen, Bernard Peissel, Tanja Pejovic, Liisa M. Pelttari, Jo Perkins, Jenny Permuth-Wey, Paolo Peterlongo, Julian Peto, Catherine M. Phelan, Kelly-Anne Phillips, Marion Piedmonte, Malcolm C. Pike, Radka Platte, Joanna Plisiecka-Halasa, Elizabeth M. Poole, Bruce Poppe, Katri Pylkäs, Paolo Radice, Susan J. Ramus, Timothy R. Rebbeck, Malcolm W.R. Reed, Gad Rennert, Harvey A. Risch, Mark Robson, Gustavo C. Rodriguez, Atocha Romero, Mary Anne Rossing, Joseph H. Rothstein, Anja Rudolph, Ingo Runnebaum, Ritu Salani, Helga B. Salvesen, Elinor J. Sawyer, Joellen M. Schildkraut, Marjanka K. Schmidt, Rita K. Schmutzler, Andreas Schneeweiss, Minouk J. Schoemaker, Michael G. Schrauder, Fredrick Schumacher, Ira Schwaab, Giulietta Scuvera, Thomas A. Sellers, Gianluca Severi, Caroline M. Seynaeve, Mitul Shah, Martha Shrubsole, Nadeem Siddiqui, Weiva Sieh, Jacques Simard, Christian F. Singer, Olga M. Sinilnikova, Dominiek Smeets, Christof Sohn, Maria Soller, Honglin Song, Penny Soucy, Melissa C. Southey, Christa Stegmaier, Dominique Stoppa-Lyonnet, Lara Sucheston, Anthony Swerdlow, Ingvild L. Tangen, Muy-Kheng Tea, Manuel R. Teixeira, Kathryn L. Terry, Mary Beth Terry, Mads Thomassen, Pamela J. Thompson, Laima Tihomirova, Marc Tischkowitz, Amanda Ewart Toland, Rob A.E.M. Tollenaar, Ian Tomlinson, Diana Torres, Thérèse Truong, Helen Tsimiklis, Nadine Tung, Shelley S. Tworoger, Jonathan P. Tyrer, Celine M. Vachon, Laura J. Van 't Veer, Anne M. van Altena, C.J. Van Asperen, David van den Berg, Ans M.W. van den Ouweland, Helena C. van Doorn, Els Van Nieuwenhuysen, Elizabeth J. van Rensburg, Ignace Vergote, Senno Verhoef, Robert A. Vierkant, Joseph Vijai, Allison F. Vitonis, Anna von Wachenfeldt, Christine Walsh, Qin Wang, Shan Wang-Gohrke, Barbara Wappenschmidt, Maren Weischer, Jeffrey N. Weitzel, Caroline Weltens, Nicolas Wentzensen, Alice S. Whittemore, Lynne R. Wilkens, Robert Winqvist, Anna H. Wu, Xifeng Wu, Hannah P. Yang, Daniela Zaffaroni, M. Pilar Zamora, Wei Zheng, Argyrios Ziogas, Georgia Chenevix-Trench, Paul D.P. Pharoah, Matti A. Rookus, Maartje J. Hooning & Ellen L. Goode, 2015, Gynecologic Oncology

DOI: 10.1016/j.ygyno.2015.04.034

Type: article

Identification of novel genetic markers of breast cancer survival

Q. Guo, M.K. Schmidt, P. Kraft, S. Canisius, C. Chen, S. Khan, J. Tyrer, M.K. Bolla, Q. Wang, J. Dennis, K. Michailidou, M. Lush, S. Kar, J. Beesley, A.M. Dunning, M. Shah, K. Czene, H. Darabi, M. Eriksson, D. Lambrechts, C. Weltens, K. Leunen, S.E. Bojesen, B G. Nordestgaard, S.F. Nielsen, H. Flyger, J. Chang-Claude, A. Rudolph, P. Seibold, D. Flesch-Janys, C. Blomqvist, K. Aittomaki, R. Fagerholm, T.A. Muranen, F.J. Couch, J.E. Olson, C. Vachon, I.L. Andrulis, J.A. Knight, G. Glendon, A.M. Mulligan, A. Broeks, F.B. Hogervorst, C.A. Haiman, B.E. Henderson, F. Schumacher, L. Le Marchand, J.L. Hopper, H. Tsimiklis, C. Apicella, M.C. Southey, A. Cox, S.S. Cross, M.W.R. Reed, G.G. Giles, R.L. Milne, C. McLean, R. Winqvist, K. Pylkas, A. Jukkola-Vuorinen, M. Grip, M.J. Hooning, A. Hollestelle, J.W.M. Martens, A.M.W. van den Ouweland, F. Marme, A. Schneeweiss, R. Yang, B. Burwinkel, J. Figueroa, S.J. Chanock, J. Lissowska, E.J. Sawyer, I. Tomlinson, M.J. Kerin, N. Miller, H. Brenner, A.K. Dieffenbach, V. Arndt, B. Holleczek, A. Mannermaa, V. Kataja, V.-M. Kosma, J.M. Hartikainen, J. Li, J.S. Brand, K. Humphreys, P. Devilee, R.A.E.M. Tollenaar, C. Seynaeve, P. Radice, P. Peterlongo, B. Bonanni, P. Mariani, P. A. Fasching, M.W. Beckmann, A. Hein, A. B. Ekici, G. Chenevix-Trench, R. Balleine, K.-A. Phillips, J. Benitez, M.P. Zamora, J.I. Arias Perez, P. Menendez, A. Jakubowska, J. Lubinski, K. Jaworska-Bieniek, K. Durda, U. Hamann, M. Kabisch, H. U. Ulmer, T. Rudiger, S. Margolin, V. Kristensen, S. Nord, D.G. Evans, J.E. Abraham, H.M. Earl, L. Hiller, J.A. Dunn, S. Bowden, C. Berg, D. Campa, W.R. Diver, S.M. Gapstur, M.M. Gaudet, S.E. Hankinson, R.N. Hoover, A. Husing, R. Kaaks, M.J. Machiela, W. Willett, M. Barrdahl, F. Canzian, S.-F. Chin, C. Caldas, D.J. Hunter, S. Lindstrom, M. Garcia-Closas, P. Hall, D.F. Easton, D.M. Eccles, N. Rahman, H. Nevanlinna & P.D.P. Pharoah, 2015, JNCI Journal of the National Cancer Institute, 107(5), 1-9

DOI: 10.1093/jnci/djv081

Type: article

Prediction of breast cancer risk based on profiling with common genetic variants

N. Mavaddat, P.D.P. Pharoah, K. Michailidou, J. Tyrer, M.N. Brook, M.K. Bolla, Q. Wang, J. Dennis, A.M. Dunning, M. Shah, R. Luben, J. Brown, S.E. Bojesen, B.G. Nordestgaard, S.F. Nielsen, H. Flyger, K. Czene, H. Darabi, M. Eriksson, J. Peto, I. dos-Santos-Silva, F. Dudbridge, N. Johnson, M. K. Schmidt, A. Broeks, S. Verhoef, E.J. Rutgers, A. Swerdlow, A. Ashworth, N. Orr, M.J. Schoemaker, J. Figueroa, S.J. Chanock, L. Brinton, J. Lissowska, F.J. Couch, J.E. Olson, C. Vachon, V.S. Pankratz, D. Lambrechts, H. Wildiers, C. Van Ongeval, E. van Limbergen, V. Kristensen, G. Grenaker Alnaes, S. Nord, A.-L. Borresen-Dale, H. Nevanlinna, T.A. Muranen, K. Aittomaki, C. Blomqvist, J. Chang-Claude, A. Rudolph, P. Seibold, D. Flesch-Janys, P.A. Fasching, L. Haeberle, A.B. Ekici, M.W. Beckmann, B. Burwinkel, F. Marme, A. Schneeweiss, C. Sohn, A. Trentham-Dietz, P. Newcomb, L. Titus, K.M. Egan, D.J. Hunter, S. Lindstrom, R.M. Tamimi, P. Kraft, N. Rahman, C. Turnbull, A. Renwick, S. Seal, J. Li, J. Liu, K. Humphreys, J. Benitez, M. Pilar Zamora, J.I. Arias Perez, P. Menendez, A. Jakubowska, J. Lubinski, K. Jaworska-Bieniek, K. Durda, N.V. Bogdanova, N.N. Antonenkova, T. Dork, H. Anton-Culver, S.L. Neuhausen, A. Ziogas, L. Bernstein, P. Devilee, R.A.E.M. Tollenaar, C. Seynaeve, C.J. van Asperen, A. Cox, S.S. Cross, M.W.R. Reed, E. Khusnutdinova, M. Bermisheva, D. Prokofyeva, Z. Takhirova, A. Meindl, R.K. Schmutzler, C. Sutter, R. Yang, P. Schurmann, M. Bremer, H. Christiansen, T.-W. Park-Simon, P. Hillemanns, P. Guenel, T. Truong, F. Menegaux, M. Sanchez, P. Radice, P. Peterlongo, S. Manoukian, V. Pensotti, J.L. Hopper, H. Tsimiklis, C. Apicella, M.C. Southey, H. Brauch, T. Bruning, Y.-D. Ko, A. J. Sigurdson, M. M. Doody, U. Hamann, D. Torres, H.-U. Ulmer, A. Forsti, E. J. Sawyer, I. Tomlinson, M.J. Kerin, N. Miller, I.L. Andrulis, J.A. Knight, G. Glendon, A. Marie Mulligan, G. Chenevix-Trench, R. Balleine, G.G. Giles, R.L. Milne, C. McLean, A. Lindblom, S. Margolin, C.A. Haiman, B.E. Henderson, F. Schumacher, L. Le Marchand, U. Eilber, S. Wang-Gohrke, M. J. Hooning, A. Hollestelle, A.M.W. van den Ouweland, L.B. Koppert, J. Carpenter, C. Clarke, R. Scott, A. Mannermaa, V. Kataja, V.-M. Kosma, J.M. Hartikainen, H. Brenner, V. Arndt, C. Stegmaier, A. Karina Dieffenbach, R. Winqvist, K. Pylkas, A. Jukkola-Vuorinen, M. Grip, K. Offit, J. Vijai, M. Robson, R. Rau-Murthy, M. Dwek, R. Swann, K. Annie Perkins, M.S. Goldberg, F. Labreche, M. Dumont, D.M. Eccles, W.J. Tapper, S. Rafiq, E. M. John, A. S. Whittemore, S. Slager, D. Yannoukakos, A. E. Toland, S. Yao, W. Zheng, S. L. Halverson, A. Gonzalez-Neira, G. Pita, M. Rosario Alonso, N. Alvarez, D. Herrero, D.C. Tessier, D. Vincent, F. Bacot, C. Luccarini, C. Baynes, S. Ahmed, M. Maranian, C.S. Healey, J. Simard, P. Hall, D. F. Easton & M. Garcia-Closas, 2015, JNCI Journal of the National Cancer Institute, 107(5), 1-15

DOI: 10.1093/jnci/djv036

Type: article

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

Sophie Blein, Claire Bardel, Vincent Danjean, Lesley McGuffog, Sue Healey, Daniel Barrowdale, Andrew Lee, Joe Dennis, Karoline B. Kuchenbaecker, Penny Soucy, Mary Beth Terry, Wendy K. Chung, David E. Goldgar, Saundra S. Buys, Ramunas Janavicius, Laima Tihomirova, Nadine Tung, Cecilia M. Dorfling, Elizabeth J. van Rensburg, Susan L. Neuhausen, Yuan Chun Ding, Anne-Marie Gerdes, Bent Ejlertsen, Finn C Nielsen, Thomas VO Hansen, Ana Osorio, Javier Benitez, Raquel Andrés Conejero, Ena Segota, Jeffrey N Weitzel, Margo Thelander, Paolo Peterlongo, Paolo Radice, Valeria Pensotti, Riccardo Dolcetti, Bernardo Bonanni, Bernard Peissel, Daniela Zaffaroni, Giulietta Scuvera, Siranoush Manoukian, Liliana Varesco, Gabriele L. Capone, Laura Papi, Laura Ottini, Drakoulis Yannoukakos, Irene Konstantopoulou, Judy Garber, Ute Hamann, Alan Donaldson, Angela Brady, Carole Brewer, Claire Foo, D. Gareth Evans, Debra Frost, Diana Eccles, Fiona Douglas, Jackie Cook, Julian Adlard, Julian Barwell, Lisa Walker, Louise Izatt, Lucy E. Side, M. John Kennedy, Marc Tischkowitz, Mark T. Rogers, Mary E. Porteous, Patrick J. Morrison, Radka Platte, Ros Eeles, Rosemarie Davidson, Shirley Hodgson, Trevor Cole, Andrew K. Godwin, Claudine Isaacs, Kathleen Claes, Kim De Leeneer, Alfons Meindl, Andrea Gehrig, Barbara Wappenschmidt, Christian Sutter, Christoph Engel, Dieter Niederacher, Doris Steinemann, Hansjoerg Plendl, Karin Kast, Kerstin Rhiem, Nina Ditsch, Norbert Arnold, Raymonda Varon-Mateeva, Rita K. Schmutzler, Sabine Preisler-Adams, Nadja Bogdanova Markov, Shan Wang-Gohrke, Antoine de Pauw, Cédrick Lefol, Christine Lasset, Dominique Leroux, Etienne Rouleau, Francesca Damiola, Hélène Dreyfus, Laure Barjhoux, Lisa Golmard, Nancy Uhrhammer, Valérie Bonadona, Valérie Sornin, Yves-Jean Bignon, Jonathan Carter, Linda Van Le, Marion Piedmonte, Paul A. DiSilvestro, Miguel de la Hoya, Trinidad Caldes, Heli Nevanlinna, Kristiina Aittomäki, Agnes Jager, Ans M.W. van den Ouweland, Carolien M. Kets, Cora M. Aalfs, Flora E. van Leeuwen, Frans B.L. Hogervorst, Hanne E.J. Meijers-Heijboer, Jan C. Oosterwijk, Kees E.P. van Roozendaal, Matti A. Rookus, Peter Devilee, Rob B. van der Luijt, Edith Olah, Orland Diez, Alex Teulé, Conxi Lazaro, Ignacio Blanco, Jesús Del Valle, Anna Jakubowska, Grzegorz Sukiennicki, Jacek Gronwald, Jan Lubinski, Katarzyna Durda, Katarzyna Jaworska-Bieniek, Bjarni A. Agnarsson, Christine Maugard, Alberto Amadori, Marco Montagna, Manuel R. Teixeira, Amanda B. Spurdle, William Foulkes, Curtis Olswold, Noralane M. Lindor, Vernon S. Pankratz, Csilla I Szabo, Anne Lincoln, Lauren Jacobs, Marina Corines, Mark Robson, Joseph Vijai, Andreas Berger, Anneliese Fink-Retter, Christian F. Singer, Christine Rappaport, Daphne Geschwantler Kaulich, Georg Pfeiler, Muy-Kheng Tea, Mark H. Greene, Phuong L. Mai, Gad Rennert, Evgeny N. Imyanitov, Anna Marie Mulligan, Gord Glendon, Irene L. Andrulis, Sandrine Tchatchou, Amanda Ewart Toland, Inge Sokilde Pedersen, Mads Thomassen, Torben A. Kruse, Uffe Birk Jensen, Maria A. Caligo, Eitan Friedman, Jamal Zidan, Yael Laitman, Annika Lindblom, Beatrice Melin, Brita Arver, Niklas Loman, Richard Rosenquist, Olufunmilayo I. Olopade, Robert L. Nussbaum, Susan J. Ramus, Katherine L. Nathanson, Susan M. Domchek, Timothy R. Rebbeck, Banu K. Arun, Gillian Mitchell, Beth Y. Karlan, Jenny Lester, Sandra Orsulic, Dominique Stoppa-Lyonnet, Gilles Thomas, Jacques Simard, Fergus J. Couch, Kenneth Offit, Douglas F. Easton, Georgia Chenevix-Trench, Antonis C. Antoniou, Sylvie Mazoyer, Catherine M. Phelan, Olga M. Sinilnikova & David G. Cox, 2015, Breast Cancer Research, 17(1), 1-15

DOI: 10.1186/s13058-015-0567-2

Type: article

Common germline polymorphisms associated with breast cancer-specific survival

Ailith Pirie, Qi Guo, Peter Kraft, Sander Canisius, Diana M. Eccles, Nazneen Rahman, Heli Nevanlinna, Constance Chen, Sofia Khan, Jonathan Tyrer, Manjeet K. Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Michael Lush, Alison M. Dunning, Mitul Shah, Kamila Czene, Hatef Darabi, Mikael Eriksson, Dieter Lambrechts, Caroline Weltens, Karin Leunen, Chantal van Ongeval, Børge G. Nordestgaard, Sune F. Nielsen, Henrik Flyger, Anja Rudolph, Petra Seibold, Dieter Flesch-Janys, Carl Blomqvist, Kristiina Aittomäki, Rainer Fagerholm, Taru A. Muranen, Janet E. Olsen, Emily Hallberg, Celine Vachon, Julia A. Knight, Gord Glendon, Anna Marie Mulligan, Annegien Broeks, Sten Cornelissen, Christopher A. Haiman, Brian E. Henderson, Frederick Schumacher, Loic Le Marchand, John L. Hopper, Helen Tsimiklis, Carmel Apicella, Melissa C. Southey, Simon S. Cross, Malcolm W.R. Reed, Graham G. Giles, Roger L. Milne, Catriona McLean, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Mervi Grip, Maartje J Hooning, Antoinette Hollestelle, John WM Martens, Ans MW van den Ouweland, Federick Marme, Andreas Schneeweiss, Rongxi Yang, Barbara Burwinkel, Jonine Figueroa, Stephen J. Chanock, Jolanta Lissowska, Elinor J. Sawyer, Ian Tomlinson, Michael J. Kerin, Nicola Miller, Hermann Brenner, Katja Butterbach, Bernd Holleczek, Vesa Kataja, Veli-Matti Kosma, Jaana M. Hartikainen, Jingmei Li, Judith S. Brand, Keith Humphreys, Peter Devilee, Robert A.E.M. Tollenaar, Caroline Seynaeve, Paolo Radice, Paolo Peterlongo, Siranoush Manoukian, Filomena Ficarazzi, Matthias W Beckmann, Alexander Hein, Arif B Ekici, Rosemary Balleine, Kelly-Anne Phillips, Javier Benitez, M Pilar Zamora, Jose Ignacio Arias Perez, Primitiva Menéndez, Anna Jakubowska, Jan Lubinski, Jacek Gronwald, Katarzyna Durda, Ute Hamann, Maria Kabisch, Hans Ulrich Ulmer, Thomas Rüdiger, Sara Margolin, Vessela Kristensen, Siljie Nord, D Gareth Evans, Jean Abraham, Helena Earl, Christopher J. Poole, Louise Hiller, Janet A. Dunn, Sarah Bowden, Rose Yang, Daniele Campa, W. Ryan Diver, Susan M. Gapstur, Mia M Gaudet, Susan Hankinson, Robert N. Hoover, Anika Hüsing, Rudolf Kaaks, Mitchell J. Machiela, Walter Willett, Myrto Barrdahl, Federico Canzian, Suet-Feung Chin, Carlos Caldas, David J. Hunter, Sara Lindstrom, Montserrat Garcia-Closas, Fergus J. Couch, Georgia Chenevix-Trench, Arto Mannermaa, Irene L. Andrulis, Per Hall, Jenny Chang-Claude, Douglas F. Easton, Stig E. Bojesen, Angela Cox, Peter A. Fasching, Paul D.P. Pharoah & Marjanka K. Schmidt, 2015, Breast Cancer Research, 17(1), 1-35

DOI: 10.1186/s13058-015-0570-7

Type: article

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients.

Rainer Fagerholm, Marjanka K. Schmidt, Sofia Khan, Sajjad Rafiq, William Tapper, Kristiina Aittomäki, Dario Greco, Tuomas Heikkinen, Taru A. Muranen, Peter A. Fasching, Wolfgang Janni, Richard Weinshilboum, Christian R. Loehberg, John L. Hopper, Melissa C. Southey, Renske Keeman, Annika Lindblom, Sara Margolin, Arto Mannermaa, Vesa Kataja, Georgia Chenevix-Trench, Diether Lambrechts, Hans Wildiers, Jenny Chang-Claude, Petra Seibold, Fergus J. Couch, Janet E. Olson, Irene L. Andrulis, Julia A. Knight, Montserrat García-Closas, Jonine Figueroa, Maartje J. Hooning, Agnes Jager, Mitul Shah, Barbara J. Perkins, Robert Luben, Ute Hamann, Maria Kabisch, Kamila Czene, Per Hall, Douglas F. Easton, Paul D.P. Pharoah, Jianjun Liu, Diana Eccles, Carl Blomqvist & Heli Nevanlinna, 2015, Oncotarget, 6(10), 7390-7407

DOI: 10.18632/oncotarget.3506

Type: article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

Timothy R. Rebbeck, Nandita Mitra, Fei Wan, Olga M. Sinilnikova, Sue Healey, Lesley McGuffog, Sylvie Mazoyer, Georgia Chenevix-Trench, Douglas F. Easton, Antonis C. Antoniou, Katherine L. Nathanson, Yael Laitman, Anya Kushnir, Shani Paluch-Shimon, Raanan Berger, Jamal Zidan, Eitan Friedman, Hans Ehrencrona, Marie Stenmark-Askmalm, Zakaria Einbeigi, Niklas Loman, Katja Harbst, Johanna Rantala, Beatrice Melin, Dezheng Huo, Olufunmilayo I. Olopade, Joyce Seldon, Patricia A. Ganz, Robert L. Nussbaum, Salina B. Chan, Kunle Odunsi, Simon A. Gayther, Susan M. Domchek, Banu K. Arun, Karen H. Lu, Gillian Mitchell, Beth Y. Karlan, Christine Walsh, Jenny Lester, Andrew K. Godwin, Harsh Pathak, Eric Ross, Mary B. Daly, Alice S. Whittemore, Esther M. John, Alexander Miron, Mary Beth Terry, Wendy K. Chung, David E. Goldgar & Diana Eccles, 2015, JAMA, 313(13), 1347-1361

DOI: 10.1001/jama.2014.5985

Type: article

Professor Diana Eccles

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