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Dr Jonathan West

Associate Professor

Research interests

  • Time-Resolved Structural Biology The emergence of serial crystallography brings many exciting possibilities for structural biology but also brings the challenge of preparing many thousands of sub-micron crystals. To address this, we are working with Ivo Tews and Allen Orville to develop high throughput droplet microfluidic systems. Here volumetric confinement of the phase diagram defines growth limits for producing monodisperse protein crystals. Beyond this, the microfluidic processors can be interfaced with the beam line to enable dynamic structural biology.

More research

Accepting applications from PhD students.

Connect with Jonathan

Email: [email protected]

Tel: +44 23 8059 3460

ORCID

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About

"Discovery-driven engineering: I develop microfluidic methods for gaining new insights into biological systems"

Research in my lab focusses on the development of high throughput microfluidic approaches for cell and molecular handling. My microfluidic toolkit ever evolves, with droplet, inertial and compartmentalised microfluidic platforms currently being the core technologies in my lab. Allied with these, an open instrumentation approach is used to provide microfluidic workstations in the labs of collaborators. My overall approach involves the development of analytical pipelines coupling the microfluidic processors with state of the art cytometry, imaging, RNA-Seq, mass spectrometry and beam line techniques to deliver high quality data sets enabling new insights into biological systems.

You can update this in Pure (opens in a new tab). Select ‘Edit profile’. Under the heading and then ‘Curriculum and research description’, select ‘Add profile information’. In the dropdown menu, select - ‘About’.

Write about yourself in the third person. Aim for 100 to 150 words covering the main points about who you are and what you currently do. Clear, simple language is best. You can include specialist or technical terms.

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