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Southampton Clinical Trials Unit (SCTU)

Explore a selection of our current and past research projects.

A DAVIES - A Phase 1b/11 combination of ACP-196 with Rituximiab, Cyclophosphamide, doxorubicin, Vincristine and Prenisolone (R-CHOP) for patients with Diffused B-cell Lymphoma (DLBCL) - "ACCEPT" - ACP-196 - ACERTA

A multicentre randomised controlled trial (RCT) of a uro-oncology clinical nurse specialist (CNS) team delivered cognitive behavioural therapy (CBT) intervention to reduce the impact of hot flush and night sweat (HFNS) symptoms in men with prostate cancer

An open, prospective Phase III clinical study to compare polatuzumab vedotin plus rituximab, ifosfamide, carboplatin and etoposide (PolaRICE) with rituximab, ifosfamide, carboplatin and etoposide (RICE)

Cellulitis optimal antibiotic treatment (COAT) study

CTU - CCTG- Crabb - A RANDOMIZED PHASE II TRIAL ASSESSING TRIMODALITY THERAPY WITH OR WITHOUT ADJUVANT DURVALUMAB TO TREAT PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER

ELECTRA (intraoperativE eLECtron radioTherapy in Rectal cAncer): A single-blinded feasibility study of intraoperative electron beam radiotherapy in patients with locally advanced or locally recurrent rectal cancer

Optimizing MATrix as remission induction treatment for newly diagnosed primary CNS Lymphoma – a randomized phase III trial (OPTIMATE trial)

PHASED IN - PHarmacy partnership using decision-making tools and near patient testing for Antimicrobial Stewardship for EveryDay practice IN primary care

ECO Eczema Care Online

SAFA study (Spironolactone for Adult Female Acne)