Research group

Interdisciplinary Musculoskeletal Health

4 Stained femur cross sections

The University hosts a substantial interdisciplinary community of researchers working to transform musculoskeletal health across the life course.

About

With expertise in regenerative medicine, physiology, engineering, orthopaedics, prosthetics and orthotics, rehabilitation and assistive technologies, epidemiology and clinical trial design, we aim to improve lives by delivering improved treatments, increasing the speed to market of musculoskeletal-focused technology and training the next generation of scientists and engineers. 

The population across the globe is living longer, which brings a number of healthcare challenges, especially in musculoskeletal health. The burden of age-related disease and injury is rising rapidly, having a detrimental impact on people’s quality of life and increasing the costs of healthcare provision. Loss of muscle mass and function is the leading reason for loss of independence in later life, and causes impaired mobility, falls, fractures, physical disability, increased insulin resistance and associated co-morbidities, and mortality. The number of hip fractures is expected to rise to 6.3 million by 2050 and the number of diabetic lower limb amputations has now risen to 7,000 per year in the UK and over 70,000 in the USA. 

The University is working to meet these challenges by creating networks of experts working in interdisciplinary musculoskeletal health research to develop new technologies, interventions and practices that will have a positive effect on people’s lives:

  • FortisNet is an interdisciplinary research network of clinical, academic and industrial partners that aims to develop products and services to transform musculoskeletal health. Launched in 2016, we have fostered over 50 new collaborations with other universities from across the UK, the NHS and industry. We have developed courses with national partners to help innovators understand how to bring medical technologies to market, and through investment in interdisciplinary studentships we are working to dissolve discipline boundaries, to train a new generation of life scientists and engineers for the benefit of society.
  • MyAge (Muscle resilience across the life course: from cells to society) is one of eleven UK Ageing Networks, funded by the Biotechnology and Biological Sciences Research Council and Medical Research Council. Led by the Institute for Life Sciences, together with partners from Birmingham, Nottingham and Imperial, the network will guide the future of muscle resilience research through roadmap development and interdisciplinary collaboration.

Research highlights

Preventing the transmission of non-communicable disease risk between generations

Research from the Developmental Origins of Health and Disease Centre demonstrates how the diet and lifestyle choices of prospective parents and pregnant mothers can affect the long-term health of their children.

Using nanoclay gel to regrow, repair and replace damaged cells

Southampton researchers have developed an innovative medical clay that can be used to apply regenerative medicine to patients with musculoskeletal conditions.

People, projects and publications

People

Professor Keith Godfrey

Associate Dean Enterprise
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Dr Kelvin Peh

Assoc Professor of Conservation Science

Research interests

  • Kelvin Peh’s interests range from forest ecology to urban wildlife in respect of diversity and distribution. He is interested in all areas of wildlife-human conflicts and wildlife ecology in human-dominated landscapes, and in the application of his research results to the conservation/management of biological resources.
  • Tropical Forest Ecology – Kelvin’s work on monodominance in tropical tree-dominated systems - has helped rekindle scientific interest in this fascinating, yet relatively unexplored phenomenon in tropical forests. He is the principal editor of the “Routledge Handbook of Forest Ecology Second Edition”, published by Routledge under its “Earthscan” imprint on 7 October 2024 (available at www.routledge.com/9781032348384).
  • Ecosystem Services – Kelvin is best known for his leading role in the development of TESSA (Toolkit for Ecosystem Service Site-based Assessment). TESSA v3.0, published on 31 Oct 2022, is now available at https://www.birdlife.org/tessa-tools/. For the impacts of TESSA, see: https://bit.ly/4ccpken. He continues working on this ecosystem service assessment project to develop and test novel tools for rapidly assessing the net impact of site-based conservation on the provision of ecosystem services. This project runs in collaboration with the University of Cambridge, the Royal Society for the Protection of Birds, BirdLife International, Tropical Biology Association, Anglia Ruskin University and UNEP-World Conservation Monitoring Centre. Currently, he is leading the ecosystem service task team of the Asian Development Bank’s Regional Flyway Initiative.

Accepting applications from PhD students

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Dr Kif Liakath-Ali MSc, MPhil, PhD.

Lecturer in Advanced Cell Biology

Research interests

  • Regulation of RNA splicing
  • RNA Splicing Misregulation in Neurodegeneration
  • Ribosomes and Alternative Splicing

Accepting applications from PhD students

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Dr Kirsten Poore

Principal Teaching Fellow
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Professor Koushik Maharatna PhD

Prof Signal Processing System Design
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Dr Leisle Ezekiel PhD

Lecturer

Accepting applications from PhD students

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Dr Lex Kraaijeveld

Principal Teaching Fellow
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Dr Libo Li

Lecturer in Business Analytics

Research interests

  • Time-to-event analysis
  • Text analytics
  • Network analytics 

Accepting applications from PhD students

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Dr Liku Tezera BM, MSc , PhD, FHEA

Senior Research Fellow
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Dr Lindsey Cherry PhD, FFPM RCSP (Glasg.), FHEA, BSc (hons)

Associate Professor

Accepting applications from PhD students

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Related research institutes, centres and groups

Related research institutes, centres and groups

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We welcome new members. To join, or find out more about FortisNet or MyAge, please email the Institute for Life Sciences team.