About
Patrick joined the Cancer Sciences School in 2006 to create a Protein Facility. As of 2024, he has 30 years of experience in molecular biology and 20 years of experience in protein expression and protein purification.
The Protein Facility has produced over 100 different proteins and Patrick has contributed to over 45 publications.
Research
Research groups
Member of:
Research interests
- Cancer immunotherapy
- Production of recombinant proteins
Current research
The Protein Facility is focused on the production of recombinant proteins involved in cancer. The process involves all the steps from cloning and expression to purification and quality control.
The Protein Facility has strong interactions with structure biologists in the Institute of Life Sciences.
Publications
38 publications
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Osman Dadas, Joel D. Allen, Sarah L. Buchan, Jinny H. Kim, H.T. Claude Chan, C. Ian Mockridge, Patrick J. Duriez, Anne Rogel, Max Crispin & Aymen Al-Shamkhani,
2023, Frontiers in Immunology, 14
Type: article
Joseph Richard Stephenson Clarke, Leon R Douglas, Patrick Duriez, Dimitrios-Ilias Balourdas, Andreas C. Joerger, Raniya Khadiullina, Emil Bulatov & Matthias G.J. Baud,
2022, ACS Pharmacology and Translational Science, 5(11), 1169–1180
Type: article
Denise Boulanger, Leon R Douglas, Patrick Duriez, Yoyel Kang, Neil Dalchau, Edward James & Tim Elliott,
2022, Frontiers in Immunology, 13
Type: article
Christian M. Orr, Hayden Fisher, Xiaojie Yu, Claude H.T. Chan, Yunyun Gao, Patrick Duriez, Steven Booth, Isabel, Grace Elliott, Tatyana Inzhelevskaya, Christopher Mockridge, Christine Penfold, Armin Wagner, Martin Glennie, Ann L White, Jonathan W. Essex, Arwen R. Pearson, Mark Cragg & Ivo Tews,
2022, Science immunology, 7(73), 1-11
Type: article
Maria Humbert, Precious Opurum, Nathan Brendish, Stephen Poole, Peijun He, Ioannis Katis, Jerry Quaye, Yaw Bediako, Patrick Duriez, R.W. Eason, Collin Sones, Osbourne Quaye, Gordon Awandare, Myron Christodoulides, Tristan Clark, Peter Quashie & Christopher Mccormick,
2022, Journal of Infection, 84(1), 48-55
Type: article
Giorgia Chiodin, Joel D Allen, Dean Bryant, Philip Rock, Enrica Antonia Martino, Beatriz Valle-Argos, Patrick J Duriez, Yasunori Watanabe, Isla Henderson, James S Blachly, Katy J McCann, Jonathan C Strefford, Graham Packham, Teunis Bh Geijtenbeek, Carl Figdor, George Wright, Louis Michael Staudt, Richard Burack, Thomas Bowden, Max Crispin, Freda Kathryn Stevenson & Francesco Forconi,
2021, Blood, 138(17), 1570-1582
Type: article
Xiaojie Yu, Sonya James, James H. Felce, Blanka Kellermayer, David A. Johnston, H. T.Claude Chan, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Yasunori Watanabe, Max Crispin, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Martin J. Glennie & Mark S. Cragg,
2021, Communications Biology, 4(1), 772
Type: article
Beatriz Valle-Argos, Giorgia Chiodin, Dean Bryant, Joe Taylor, Elizabeth Lemm, Patrick Duriez, Philip J Rock, Jonathan Strefford, Francesco Forconi, Richard Burack, Graham Packham & Freda Stevenson,
2021, Scientific Reports, 11(1)
Type: article
Maria Teresa Borrello, Hanae Benelkebir, Adam Lee, Chak Hin Tam, Manar Shafat, Stuart A. Rushworth, Kristian M. Bowles, Leon Douglas, Patrick J. Duriez, Sarah Bailey, Simon J. Crabb, Graham Packham & A. Ganesan,
2021, ChemMedChem, 16(8), 1316-1324
Type: article
Xiaojie Yu, H. T.Claude Chan, Hayden Fisher, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Vikki English, J. Sjef Verbeek, Ann L. White, Ivo Tews, Martin J. Glennie & Mark S. Cragg,
2020, Cancer Cell, 37(6), 850-866.e7
Type: article