About
Patrick joined the Cancer Sciences School in 2006 to create a Protein Facility. As of 2024, he has 30 years of experience in molecular biology and 20 years of experience in protein expression and protein purification.
The Protein Facility has produced over 100 different proteins and Patrick has contributed to over 45 publications.
Research
Research groups
Member of:
Research interests
- Cancer immunotherapy
- Production of recombinant proteins
Current research
The Protein Facility is focused on the production of recombinant proteins involved in cancer. The process involves all the steps from cloning and expression to purification and quality control.
The Protein Facility has strong interactions with structure biologists in the Institute of Life Sciences.
Publications
38 publications
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A1 functions at the mitochondria to delay endothelial apoptosis in response to tumor necrosis factor
Patrick J. Duriez, Fred Wong, Katerina Dorovini-Zis, Reza Shahidi & Aly Karsan,
2000, The Journal of Biological Chemistry, 275(24), 18099-18107
Type: article
El B. Affar, Patrick J. Duriez, Rashmi G. Shah, Eric Winstall, Marc Germain, Claudia Boucher, Sylvie Bourassa, James B. Kirkland & Guy G. Poirier,
1999, Biochimica et Biophysica Acta (BBA) - Biomembranes, 1428(2-3), 137-146
Type: article
David K. Perry, Mirrian J. Smyth, Henning R. Stennicke, Guy S. Salvesen, Patrick Duriez, Guy G. Poirier & Yusuf A. Hannun,
1997, The Journal of Biological Chemistry, 272(30), 18530-18533
Type: article
Damien D'Amours, Patrick J. Duriez, Kim Orth, Rashmi G. Shah, Vishva M. Dixit, William C. Earnshaw, Emad S. Alnemri & Guy G. Poirier,
1997, Analytical Biochemistry, 249(1), 106-8
Type: article
P.J. Duriez, S. Desnoyers, J.C. Hoflack, G.M. Shah, B. Morelle, S. Bourassa, G.G. Poirier & B. Talbot,
1997, Biochimica et Biophysica Acta (BBA) - Biomembranes, 1334(1), 65-72
Type: article
David K. Perry, Miriam J. Smyth, Hong-Gang Wang, John C. Reed, Patrick Duriez, Guy G. Poirier, LinaM. Obeid & Yusuf A. Hannun,
1997, Cell Death and Differentiation, 4(1), 29-33
Type: article
P.J. Duriez & G.M. Shah,
1997, Biochemistry and Cell Biology, 75(4), 337-349
DOI: 10.1139/bcb-75-4-337
Type: article
Christopher J. Froelich, William L. Hanna, Guy G. Poirier, Patrick J. Duriez, Damien D'Amours, Guy S. Salvesen, Emad S. Alnemri, William C. Earnshaw & Girish M. Shah,
1996, Biochemical and Biophysical Research Communications, 227(3), 658-665
Type: article