Project overview
The UKRMP2 Smart Materials Hub aims to develop the next generation of bioactive scaffolds and biomatrices to treat the eye, the musculoskeletal system and the liver. Regenerative medicine holds the promise of revolutionising patient care addressing the problems of an ageing population.
The Bone and Joint Research Group are part of the Acellular Smart Materials Hub with a specific focus on addressing skeletal repair and function moving from basic discovery science through to clinical translation. Research will seek to address the current unmet need for material systems that not only deliver cells safely but also provide cues for differentiation and the organisation of hierarchical and vascularised tissues. The development of materials with highly controlled spatio-temporal features that can respond to environmental triggers is also key in the quest for smarter more biomimetic solutions. The Acellular Smart materials UKRMP Programme will, over five years deliver innovative acellular material solutions to tissue regeneration with research encompassing fundamental research through to preclinical evaluation and, ultimately clinical delivery.
The Bone and Joint Research Group are part of the Acellular Smart Materials Hub with a specific focus on addressing skeletal repair and function moving from basic discovery science through to clinical translation. Research will seek to address the current unmet need for material systems that not only deliver cells safely but also provide cues for differentiation and the organisation of hierarchical and vascularised tissues. The development of materials with highly controlled spatio-temporal features that can respond to environmental triggers is also key in the quest for smarter more biomimetic solutions. The Acellular Smart materials UKRMP Programme will, over five years deliver innovative acellular material solutions to tissue regeneration with research encompassing fundamental research through to preclinical evaluation and, ultimately clinical delivery.
Staff
Other researchers
Collaborating research institutes, centres and groups
Research outputs
2020, Science Translational Medicine, 12(572)
Type: review
Yanghee Kim, Xia Yang, Liyang Shi, Stuart Lanham, Jons Hilborn, Richard Oreffo, Dmitri Ossipov & Jonathan Dawson,
2020, Nature Communications, 11(1)
Type: article
Yuanhao Wu, Babatunde O. Okesola, Jing Xu, Ivan Korotkin, Alice Berardo, Ilaria Corridori, Francesco Luigi Pellerej di Brocchetti, Janos Kanczler, Jingyu Feng, Weiqi Li, Yejiao Shi, Vladimir Farafonov, Yiqiang Wang, Rebecca F. Thompson, Maria Magdalena Titirici, Dmitry Nerukh, Sergey Karabasov, Richard O.C. Oreffo, Jose Carlos Rodriguez-Cabello, Giovanni Vozzi, Helena S. Azevedo, Nicola M. Pugno, Wen Wang & Alvaro Mata,
2020, Nature Communications, 11(1)
Type: article
Benita Scout MacKay, Matthew Praeger, James Grant-Jacob, Janos Kanczler, Robert Eason, Richard Oreffo & Benjamin Mills,
2020, Tissue and Cell, 67
Type: article
Karen Marshall, Janos Kanczler & Richard Oreffo,
2020, Journal of Tissue Engineering, 11(2041731420942734)
Type: article