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Research project

B Linclau - IB Catalyst - BB/M028941/1

Staff

Other researchers

Dr Seung Lee

Associate Professor

Research interests

  • Chemical biology
  • Antimicrobial resistance
  • Glycan processing enzymes
Connect with Seung

Email: [email protected]

Collaborating research institutes, centres and groups

Research outputs

Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands
Sarah-Jane Richards, Tessa Keenan, Jean-Baptiste Vendeville, David Wheatley, Harriet Chidwick, Darshita Budhadev, Claire Council, Claire S. Webster, Helene Ledru, Alexander Baker, Marc Walker, M. Carmen Galan, Bruno Linclau, Martin A. Fascione & Matthew I. Gibson, 2020, Chemical Science, 12(3), 905-910
DOI: 10.1039/D0SC05360K
Type: article
Profiling substrate promiscuity of wild-type sugar kinases for multifluorinated monosaccharides
2020, Cell Chemical Biology, 27(9), 1199-1206.e5
DOI: 10.1016/j.chembiol.2020.06.005
Type: article
Chemoenzymatic synthesis of 3-deoxy-3-fluoro-L-fucose and its enzymatic incorporation into glycoconjugates
Pablo Valverde Sanchez, Jean B Vendeville, Kristian Hollingsworth, Ashley Mattey, Tessa Keenan, Harriet Chidwick, Helene Ledru, Kler Huonnic, Kun Huang, Mark Light, Nicholas Turner, Jesus Jimenez-Barbero, M. Carmen Galan, Martin A. Fascione, Sabine L. Flitsch, W. Bruce Turnbull & Bruno Linclau, 2020, Chemical Communications, 56(47), 6408-6411
DOI: 10.1039/d0cc02209h
Type: article
Enzymatic glycosylation involving fluorinated carbohydrates
Claire Council, Kelly J. Kilpin, Jessica S Gusthart, Sarah A. Allman, Bruno Linclau & Seung Seo Lee, 2020, Organic & Biomolecular Chemistry, 18(18), 3423-3451
DOI: 10.1039/D0OB00436G
Type: article
Molecular insights into DC-SIGN binding to self-antigens: the interaction with the blood group A/B antigens
2019, ACS Chemical Biology, 14(7), 1660-1671
DOI: 10.1021/acschembio.9b00458
Type: article