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Research project

Establishment of a National Network on Musculoskeletal Ageing

Staff

Lead researcher

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: [email protected]

Other researchers

Professor Nicholas Harvey

Director/Professor

Research interests

  • Lifecourse epidemiology of osteoporosis and fragility fractures
  • Understanding mechanism and development of novel interventions across lifecourse to prevent fragility fractures
Connect with Nicholas

Email: [email protected]

Collaborating research institutes, centres and groups

Interdisciplinary Musculoskeletal Health

The University hosts a substantial interdisciplinary community of researchers working to transform musculoskeletal health across the life course.

Research outputs

Novel formulations of oral bisphosphonates in the treatment of osteoporosis
Nicholas Fuggle, Nasser Al-Daghri, Olivier Bock, Jaime Branco, Olivier Bruyère, Enrique Casado, Etienne Cavalier, Bernard Cortet, Maarten de Wit, Andrea Giusti, Philippe Halbout, Nicholas C Harvey, Mickaël Hiligsmann, Jean-Marc Kaufman, Andreas Kurth, Stefania Maggi, Radmila Matijevic, Salvatore Minisola, Santiago Palacios, Régis Pierre Radermecker, Friederike Thomasius, Sansin Tuzun, Nicola Veronese, John A Kanis, Jean-Yves Reginster, René Rizzoli & Cyrus Cooper, 2022, Aging Clinical and Experimental Research, 34(11), 2625-2634
DOI: 10.1007/s40520-022-02272-z
Type: review
A review of epigenetics and its association with ageing of muscle and bone.
Nicholas Fuggle, Faidra Laskou, Nicholas Harvey & Elaine Dennison, 2022, Maturitas, 165, 12-17
DOI: 10.1016/j.maturitas.2022.06.014
Type: review
Determinants of muscle density and clinical outcomes: findings from the Hertfordshire Cohort Study
Faidra Laskou, Leo Westbury, Nicholas Fuggle, Nicholas Harvey, Harnish Patel, Cyrus Cooper, Kate Ward & Elaine Dennison, 2022, Bone, 164
DOI: 10.1016/j.bone.2022.116521
Type: article
Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability - results from the Women's Health Initiative hormone therapy trials
Mattias Lorentzen, Helena Johansson, Nicholas Harvey, Enwu Liu, Liesbeth Vandenput, Carolyn J. Crandall, Jane A. Cauley, Meryl S. LaBoff, E.V. McCloskey & John A. Kanis, 2022, Osteoporosis International, 33(11), 2297-2305
DOI: 10.1007/s00198-022-06483-y
Type: article
Role of Vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
Thierry Chevalley, M.L. Brandi, Kevin D. Cashman, Etienne Cavalier, Nicholas Harvey, Stefania Maggi, Cyrus Cooper, Nasser M. Al-Daghri, Oliver Bock, Olivier Bruyère, Mario M. Rosa, B. Cortet, Alfonso Jose Cruz-Jentoft, Antonio Cherubini, Bess Dawson-Hughes, Roger A. Fielding, Nicholas Fuggle, Philippe Halbout, John A. Kanis, J.M. Kaufman, Olivier Lamy, Andrea Laslop, María Concepción  Prieto Yerro, Regis Pierre Rademecker, Jotheeswaran Amuthavalli Thiyagarajan, Thierry Thomas, Nicola Veronese, Marten de Wit, Jean Yves Reginster & Rene Rizzoli, 2022, Aging Clinical and Experimental Research, 34(11), 2603-2623
DOI: 10.1007/s40520-022-02279-6
Type: review