Research project

Investigating the role of PIP4K2B, nuclear phosphoinositides and TAF3 in transcription and genome organisation during myogenic differentiation

Lead researchers:

Professor Nullin Divecha
Research funder:

Biotechnology & Biological Sciences Research Council
Status:

Not active

Staff

Lead researchers

Professor Nullin Divecha

Professor of Cellular Signalling

Connect with Nullin

Email: [email protected]

Research outputs

Exploring the controversial role of PI3K signalling in CD4+ regulatory T (T-Reg) cells

Alessandro Poli, Roberta Fiume, Sara Mongiorgi, Antonio Zaurito, Bhavwanti Sheth, Magdalena Castellano Vidalle, Shidqiyyah Abdul Hamid, Scottt. Kimber, Francesca Campagnoli, Stefano Ratti, Isabella Rusciano, Irene Faenza, Lucia Manzoli & Nullin Divecha, 2020, Advances in Biological Regulation, 76, 100722

DOI: 10.1016/j.jbior.2020.100722

Type: article

Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial-mesenchymal transition and subcellular re-localization of Beta-Catenin

Emily H. Bowler, Alex Smith-Vidal, Alex Lester, Joseph Bell, Zhenghe Wang, Christopher Bell, Yihua Wang, Nullin Divecha, Paul Skipp & Rob M. Ewing, 2019, Epigenetics, 15(1-2), 107-121

DOI: 10.1080/15592294.2019.1656154

Type: article

Nuclear phosphoinositides

R. Fiume, I. Faenza, B. Sheth, A. Poli, M. C. Vidalle, C. Mazzetti, S. H. Abdul, F. Campagnoli, M. Fabbrini, S. T. Kimber, G. A. Mariani, J. Xian, M. V. Marvi, S. Mongiorgi, Z. Shah & N. Divecha, 2019, International Journal of Molecular Sciences, 20(12)

DOI: 10.3390/ijms20122991

Type: review

Phosphatidylinositol 5 phosphate (Pi5p)

Alessandro Poli, Antonio Enrico Zaurito, Shidqiyyah Abdul-Hamid, Roberta Fiume, Irene Faenza & Nullin Divecha, 2019, International Journal of Molecular Sciences, 20(9)

DOI: 10.3390/ijms20092080

Type: review

Proteomic analysis of azacitidine-induced degradation profiles identifies multiple chromatin and epigenetic regulators including Uhrf1 and Dnmt1 as sensitive to azacitidine

Emily H. Bowler, Joseph Bell, Nullin Divecha, Paul Skipp & Rob M. Ewing, 2019, Journal of Proteome Research, 18(3), 1032-1042

DOI: 10.1021/acs.jproteome.8b00745

Type: article