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Research project

Photo-Electro: Transforming Chemical Synthesis, Discovery and Manufacture

Staff

Lead researcher

Professor Richard Brown

Professor of Organic Chemistry

Research interests

  • Organic synthesis
  • Total synthesis of natural products
  • Asymmetric synthesis
Connect with Richard

Email: [email protected]

Other researchers

Professor David Harrowven

Professor of Chemistry

Research interests

  • Organic synthesis
  • Natural products total synthesis
  • Radical and diradical chemistry
Connect with David

Email: [email protected]

Collaborating research institutes, centres and groups

Organic Chemistry, Synthesis, Catalysis

We develop environmentally sustainable approaches to chemical manufacture that minimise chemical waste, improve product velocity and reduce the need to isolate intermediates.

Research outputs

Cathodic radical cyclisation of aryl halides using a strongly-reducing catalytic mediator in flow
Ana Folgueiras Amador, Alexander Teuten, Mateo Salam Perez, James Pearce, Guy Denuault, Derek Pletcher, Phillip James Parsons, David C. Harrowven & Richard C.D. Brown, 2022, Angewandte Chemie International Edition, 61(35)
DOI: 10.1002/anie.202203694
Type: article
First example of organocatalysis by cathodic N-heterocyclic carbene generation and accumulation using a divided electrochemical flow cell
Daniele Rocco, Ana Folgueiras Amador, Richard C.D. Brown & Marta Feroci, 2022, Beilstein Journal of Organic Chemistry, 18, 979-990
DOI: 10.3762/bjoc.18.98
Type: article
New Approaches to Ondansetron and Alosetron Inspire a Versatile, Flow Photochemical Method for Indole Synthesis
Wei Sun, William Raimbach, Luke D. Elliott, Kevin I. Booker-Milburn & David C. Harrowven, 2022, ChemComm, 58(3), 383-386
DOI: 10.1039/D1CC05700F
Type: article
Self-optimization of continuous flow electrochemical synthesis using Fourier transform infrared spectroscopy and gas chromatography
Jie Ke, Chuang Gao, Ana A. Folgueiras-Amador, Katherine E. Jolley, Oscar de Frutos, Carlos Mateos, Juan A. Rincón, Richard C.D. Brown, Martyn Poliakoff & Michael W. George, 2022, Applied Spectroscopy, 76(1), 38-50
DOI: 10.1177/00037028211059848
Type: article
Wavelength dependent photoextrusion and tandem photoextrusion reactions of ninhydrin bis-acetals for the synthesis of 8-ring lactones, benzocyclobutenes and orthoanhydrides
David C. Harrowven, Wei Sun, Surajit Kayal, William Raimbach, Xue-Zhong Sun, Mark Light, Magnus W.D. Hanson-Heine & Michael W George, 2021, ChemComm
DOI: 10.1039/D1CC06800H
Type: article