Research project

The role of nuclear phosphoinositides in epigenetic signalling - N Divecha - BBSRC

Lead researchers:

Professor Nullin Divecha
Research funder:

Biotechnology & Biological Sciences Research Council
Status:

Not active

Staff

Lead researchers

Professor Nullin Divecha

Professor of Cellular Signalling

Connect with Nullin

Email: [email protected]

Research outputs

Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial-mesenchymal transition and subcellular re-localization of Beta-Catenin

Emily H. Bowler, Alex Smith-Vidal, Alex Lester, Joseph Bell, Zhenghe Wang, Christopher Bell, Yihua Wang, Nullin Divecha, Paul Skipp & Rob M. Ewing, 2019, Epigenetics, 15(1-2), 107-121

DOI: 10.1080/15592294.2019.1656154

Type: article

Nuclear phosphoinositides

R. Fiume, I. Faenza, B. Sheth, A. Poli, M. C. Vidalle, C. Mazzetti, S. H. Abdul, F. Campagnoli, M. Fabbrini, S. T. Kimber, G. A. Mariani, J. Xian, M. V. Marvi, S. Mongiorgi, Z. Shah & N. Divecha, 2019, International Journal of Molecular Sciences, 20(12)

DOI: 10.3390/ijms20122991

Type: review

Phosphatidylinositol 5 phosphate (Pi5p)

Alessandro Poli, Antonio Enrico Zaurito, Shidqiyyah Abdul-Hamid, Roberta Fiume, Irene Faenza & Nullin Divecha, 2019, International Journal of Molecular Sciences, 20(9)

DOI: 10.3390/ijms20092080

Type: review

Proteomic analysis of azacitidine-induced degradation profiles identifies multiple chromatin and epigenetic regulators including Uhrf1 and Dnmt1 as sensitive to azacitidine

Emily H. Bowler, Joseph Bell, Nullin Divecha, Paul Skipp & Rob M. Ewing, 2019, Journal of Proteome Research, 18(3), 1032-1042

DOI: 10.1021/acs.jproteome.8b00745

Type: article

Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy

Mark R. Lundquist, Marcus D. Goncalves, Ryan M. Loughran, Elite Possik, Tarika Vijayaraghavan, Annan Yang, Chantal Pauli, Archna Ravi, Akanksha Verma, Zhiwei Yang, Jared L. Johnson, Jenny C.Y. Wong, Yilun Ma, Katie Seo Kyoung Hwang, David Weinkove, Nullin Divecha, John M. Asara, Olivier Elemento, Mark A. Rubin, Alec C. Kimmelman, Arnim Pause, Lewis C. Cantley & Brooke M. Emerling, 2018, Molecular Cell, 70(3), 531–544.e9

DOI: 10.1016/j.molcel.2018.03.037

Type: article