About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Member of:
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Sponsor: Medical Research Council
Researchers:
Sponsor: Cancer Research UK
Completed projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Researchers:
Researchers:
Sponsor: Cancer Research UK
Researchers:
Sponsor: Wessex Medical Research
Publications
66 publications
Page 4 of 7
Jane Willoughby, Jordana Griffiths, Ivo Tews & Mark Cragg,
2017, Molecular Immunology, 83, 13-22
Type: article
Dom Bellini, Sam Horrell, Andrew Hutchin, Curtis W Phippen, Richard W Strange, Yuming Cai, Armin Wagner, Jeremy S Webb, Ivo Tews & Martin A Walsh,
2017, Scientific Reports, 7, 42166
DOI: 10.1038/srep42166
Type: article
Jeremy Webb, Andrew James Hutchin, Dom Bellini, Sam Horrell, Curtis Phippen, Yuming Cai, Richard W. Strange, Armin Wagner, Martin A. Walsh & Ivo Tews,
2016, Acta Crystallographica Section A: Foundations and Advances, 72(Supplement 1), S39-S40
Type: conference
Salah Mansour, Anna Tocheva, Chris Cave-Ayland, Moritz M. Machelett, Barbara Sander, Nikolai M. Lissin, Peter E. Molloy, Mark S. Baird, Gunthard Stubs, Nicolas W.J. Schroder, Ralf R. Schumann, Jorg Rademann, Anthony D. Postle, Bent K. Jakobsen, Ben G. Marshall, Rajendra Gosain, Paul Elkington, Tim Elliott, Chris-Kriton Skylaris, Jonathan W. Essex, Ivo Tews & Stephan D. Gadola,
2016, Proceedings of the National Academy of Sciences, 113(9), E1266-E1275
Type: article
Ivo Tews & Jon Cooper,
2015, Acta Crystallographica Section D: Biological Crystallography, 71, 1-2
Type: article
Curtis William Phippen, Halina Mikolajek, Henry George Schlaefli, Charles William Keevil, Jeremy Stephen Webb & Ivo Tews,
2014, FEBS Letters, 588(24), 4631-4636
Type: article
Joanna Tripp, Alexander Hahn, Patrick Koenig, Nadine Flinner, Daniela Bublak, Eva M. Brouwer, Franziska Ertel, Oliver Mirus, Irmgard Sinning, Ivo Tews & Enrico Schleiff,
2012, The Journal of Biological Chemistry, 287(29), 24164-24173
Type: article
Gabriela Guedez, Katharina Hipp, Volker Windeisen, Bianca Derrer, Martin Gengenbacher, Bettina Boettcher, Irmgard Sinning, Barbara Kappes & Ivo Tews,
2012, Structure, 20(1), 172-184
Type: article
Barbara Kappes, Ivo Tews, Alexandra Binter & Peter Macheroux,
2011, Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1814(11), 1567-1576
Type: article
Tathagata Mukherjee, Jeremiah Hanes, Ivo Tews, Steven E. Ealick & Tadhg P. Begley,
2011, Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1814(11), 1585-1596
Type: article
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)