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Research project

Dr H M Haitchi ADAM33 gene and environmental interactions in developing lungs and their involvement in the early life origin of asthma

Staff

Lead researchers

Professor Hans Michael Haitchi MD, MMed(INT), PhD, PD, MRCP(London), FHEA, PGcert

Professor

Research interests

  • Study of the asthma susceptibility gene A Disintegrin and Metalloprotease 33 (ADAM33) in early life and adult asthma and other chronic lung diseases.
  • Development of novel Anti-ADAM33 agents as potential disease modifying asthma therapy.
  • Multiomic study of the influence of the maternal environment (e.g. allergic asthma, obesity) during pregnancy on ADAM33 and other mediators and the early origin of lung disease in the Maternal Environment in Pregnancy (MEP) cohort.
Connect with Hans Michael

Email: [email protected]

Research outputs

The clinical implications of Aspergillus Fumigatus sensitization in difficult-to-treat asthma patients
Heena Mistry, Hilda Maria Ajsivinac Soberanis, Mohammad Aref Kyyaly, Adnan Azim, Clair Barber, Deborah Knight, Colin Newell, Hans Michael Haitchi, Tom Wilkinson, Peter Howarth, Grégory Seumois, Pandurangan Vijayanand, S Hasan Arshad & Ramesh J Kurukulaaratchy, 2021, Journal of Allergy and Clinical Immunology: In Practice, 9(12), 4254-4267.e10
DOI: 10.1016/j.jaip.2021.08.038
Type: article
Asthma did not increase in-hospital Covid-19 related mortality in a tertiary UK hospital
Wei Chern Gavin Fong, Florina Borca, Hang Phan, Helen E Moyses, Paddy Dennison, Ramesh J Kurukulaaratchy & Hans Michael Haitchi, 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 51(7), 939-941
DOI: 10.1111/cea.13855
Type: letterEditorial
Clinical evaluation of type 2 disease status in a real-world population of difficult to manage asthma using historic Electronic Health Care Records of Blood Eosinophil counts
Adnan Azim, Colin Newell, Clair Barber, Matthew Harvey, Deborah Knight, Anna Freeman, Wei Chern Gavin Fong, Paddy Dennison, Hans Michael Haitchi, Ratko Djukanovic, Ramesh Kurukulaaratchy & Peter Howarth, 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 51(6), 811-820
DOI: 10.1111/cea.13841
Type: article
New perspectives on difficult asthma; sex and age of asthma-onset based phenotypes
Adnan Azim, Anna Freeman, Audrey Lavenu, Heena Mistry, Hans Michael Haitchi, Colin Newell, Yueqing Cheng, Yvette Thirlwall, Matthew Harvey, Clair Barber, Katarina Pontoppidan, Paddy Dennison, S. Hasan Arshad, Ratko Djukanovic, Peter Howarth & Ramesh J. Kurukulaaratchy, 2020, The Journal of Allergy and Clinical immunology: In Practice, 8(10), 3396-3406.e4
DOI: 10.1016/j.jaip.2020.05.053
Type: article
Patient perceived barriers to exercise and their clinical associations in difficult asthma
Anna T Freeman, David Hill, Colin Newell, Helen Moyses, Adnan Azim, Deborah Knight, Laura Presland, Matthew Harvey, Hans Michael Haitchi, Alastair Watson, Karl J Staples, Ramesh J Kurukulaaratchy & Tom M A Wilkinson, 2020, Asthma Research and Practice, 6, 5
DOI: 10.1186/s40733-020-00058-6
Type: article