Research project

Dr H M Haitchi ADAM33 gene and environmental interactions in developing lungs and their involvement in the early life origin of asthma

Lead researchers:

Professor Hans Michael Haitchi
Research funder:

Medical Research Council
Status:

Not active

Staff

Lead researchers

Professor Hans Michael Haitchi MD, MMed(INT), PhD, PD, MRCP(London), FHEA, PGcert

Professor

Research interests

Study of the asthma susceptibility gene A Disintegrin and Metalloprotease 33 (ADAM33) in early life and adult asthma and other chronic lung diseases.
Development of novel Anti-ADAM33 agents as potential disease modifying asthma therapy.
Multiomic study of the influence of the maternal environment (e.g. allergic asthma, obesity) during pregnancy on ADAM33 and other mediators and the early origin of lung disease in the Maternal Environment in Pregnancy (MEP) cohort.

Connect with Hans Michael

Email: [email protected]

Research outputs

A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis

Asif Shaffiq, Hans Michael Haitchi, Yun Yung Pang, Abdullah A. Alangari, Mark G. Jones, Ben G. Marshall, Peter H. Howarth, Donna E. Davies & Katherine M.A. O'Reilly, 2012, Respirology, 17(2), 342-349

DOI: 10.1111/j.1440-1843.2011.02098.x

Type: article

Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium

Sheila M. Bell, Liqian Zhang, Angela Mendell, Yan Xu, Hans Michael Haitchi, James L. Lessard & Jeffrey A. Whitsett, 2011, Developmental Biology, 358(1), 79-90

DOI: 10.1016/j.ydbio.2011.07.020

Type: article

Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation

Yutaka Maeda, Gang Chen, Yan Xu, Hans Michael Haitchi, Lingling Du, Angela R. Keiser, Peter H. Howarth, Donna E. Davies, Stephen T. Holgate & Jeffrey A. Whitsett, 2011, American Journal of Respiratory and Critical Care Medicine, 184(4), 421-429

DOI: 10.1164/rccm.201101-0106OC

Type: article

Intersections between pulmonary development and disease

Jeffrey A. Whitsett, Hans Michael Haitchi & Yutaka Maeda, 2011, American Journal of Respiratory and Critical Care Medicine, 184(4), 401-406

DOI: 10.1164/rccm.201103-0495PP

Type: article